Regional grey matter microstructural changes and volume loss according to disease duration in multiple sclerosis patients

Abstract The spatio-temporal characteristics of grey matter (GM) impairment in multiple sclerosis (MS) are poorly understood. We used a new surface-based diffusion MRI processing tool to investigate regional modifications of microstructure, and we quantified volume loss in GM in a cohort of patients...

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Bibliographic Details
Main Authors: Elisabeth Solana, Eloy Martinez-Heras, Victor Montal, Eduard Vilaplana, Elisabet Lopez-Soley, Joaquim Radua, Nuria Sola-Valls, Carmen Montejo, Yolanda Blanco, Irene Pulido-Valdeolivas, Maria Sepúlveda, Magi Andorra, Joan Berenguer, Pablo Villoslada, E. H. Martinez-Lapiscina, Ferran Prados, Albert Saiz, Juan Fortea, Sara Llufriu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96132-x