24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease
Non-motor symptoms are now commonly recognized in Parkinson’s Disease (PD) and can include dysautonomia. Impairment of cardiovascular autonomic function can occur at any stage of PD but is typically prevalent in advanced stages or related to (anti-parkinsonian) drugs and can result in atypical blood...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-05-01
|
Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00049/full |
id |
doaj-18dfa51da2d241478afd45ebc27cd6b2 |
---|---|
record_format |
Article |
spelling |
doaj-18dfa51da2d241478afd45ebc27cd6b22020-11-24T22:53:39ZengFrontiers Media S.A.Frontiers in Neurology1664-22952013-05-01410.3389/fneur.2013.000495033224 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s DiseaseEva eStübner0Ekawat eVichayanrat1David eLow2Christopher J Mathias3Stefan eIsenmann4Carl-Albrecht eHaensch5Dept. of Neurology, University of Witten/Herdecke, HELIOS Klinikum WuppertalAutonomic and Neurovascular Medicine Unit, Division of Brain Sciences, Faculty of Medicine, Imperial College London at St Mary’s HospitalAutonomic and Neurovascular Medicine Unit, Division of Brain Sciences, Faculty of Medicine, Imperial College London at St Mary’s HospitalAutonomic and Neurovascular Medicine Unit, Division of Brain Sciences, Faculty of Medicine, Imperial College London at St Mary’s HospitalDept. of Neurology, University of Witten/Herdecke, HELIOS Klinikum WuppertalDept. of Neurology, University of Witten/Herdecke, HELIOS Klinikum WuppertalNon-motor symptoms are now commonly recognized in Parkinson’s Disease (PD) and can include dysautonomia. Impairment of cardiovascular autonomic function can occur at any stage of PD but is typically prevalent in advanced stages or related to (anti-parkinsonian) drugs and can result in atypical blood pressure (BP) readings and related symptoms such as orthostatic hypotension (OH) and supine hypertension. OH is usually diagnosed with a head-up-tilt test (HUT) or an (active) standing test (also known as Schellong test) in the laboratory, but 24 hour Ambulatory Blood Pressure Monitoring (ABPM) in a home setting may have several advantages, such as providing an overview of symptoms in daily life alongside pathophysiology as well as assessment of treatment interventions. This, however, is only possible if ABPM is administrated correctly and an autonomic protocol (including a diary) is followed. which will be discussed in this review. A 24hr ABPM does not only allow the detection of OH, if it is present, but also the assessment of cardiovascular autonomic dysfunction during and after various daily stimuli, such as postprandial and alcohol dependent hypotension, as well as exercise and drug induced hypotension. Furthermore, information about the circadian rhythm of BP and heart rate (HR) can be obtained and establish whether or not a patient has a fall of BP at night (i.e. ‘dipper’ vs. non-‘dipper’). The information about nocturnal BP may also allow the investigation or detection of disorders such as sleep dysfunction, nocturnal movement disorders and obstructive sleep apnea, which are common in PD. Additionally, a 24hr ABPM should be conducted to examine the effectiveness of OH therapy. This review will outline the methodology of 24 hr ABPM in PD, summarize findings of such studies in PD and briefly consider common daily stimuli that might affect 24 Hr ABPM.http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00049/fullCircadian RhythmParkinson’s diseasenon-invasiveorthostatic hypotensionnon-dipping24 hr ambulatory blood pressure monitoring |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Eva eStübner Ekawat eVichayanrat David eLow Christopher J Mathias Stefan eIsenmann Carl-Albrecht eHaensch |
spellingShingle |
Eva eStübner Ekawat eVichayanrat David eLow Christopher J Mathias Stefan eIsenmann Carl-Albrecht eHaensch 24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease Frontiers in Neurology Circadian Rhythm Parkinson’s disease non-invasive orthostatic hypotension non-dipping 24 hr ambulatory blood pressure monitoring |
author_facet |
Eva eStübner Ekawat eVichayanrat David eLow Christopher J Mathias Stefan eIsenmann Carl-Albrecht eHaensch |
author_sort |
Eva eStübner |
title |
24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease |
title_short |
24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease |
title_full |
24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease |
title_fullStr |
24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease |
title_full_unstemmed |
24 hr non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s Disease |
title_sort |
24 hr non-invasive ambulatory blood pressure and heart rate monitoring in parkinson’s disease |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neurology |
issn |
1664-2295 |
publishDate |
2013-05-01 |
description |
Non-motor symptoms are now commonly recognized in Parkinson’s Disease (PD) and can include dysautonomia. Impairment of cardiovascular autonomic function can occur at any stage of PD but is typically prevalent in advanced stages or related to (anti-parkinsonian) drugs and can result in atypical blood pressure (BP) readings and related symptoms such as orthostatic hypotension (OH) and supine hypertension. OH is usually diagnosed with a head-up-tilt test (HUT) or an (active) standing test (also known as Schellong test) in the laboratory, but 24 hour Ambulatory Blood Pressure Monitoring (ABPM) in a home setting may have several advantages, such as providing an overview of symptoms in daily life alongside pathophysiology as well as assessment of treatment interventions. This, however, is only possible if ABPM is administrated correctly and an autonomic protocol (including a diary) is followed. which will be discussed in this review. A 24hr ABPM does not only allow the detection of OH, if it is present, but also the assessment of cardiovascular autonomic dysfunction during and after various daily stimuli, such as postprandial and alcohol dependent hypotension, as well as exercise and drug induced hypotension. Furthermore, information about the circadian rhythm of BP and heart rate (HR) can be obtained and establish whether or not a patient has a fall of BP at night (i.e. ‘dipper’ vs. non-‘dipper’). The information about nocturnal BP may also allow the investigation or detection of disorders such as sleep dysfunction, nocturnal movement disorders and obstructive sleep apnea, which are common in PD. Additionally, a 24hr ABPM should be conducted to examine the effectiveness of OH therapy. This review will outline the methodology of 24 hr ABPM in PD, summarize findings of such studies in PD and briefly consider common daily stimuli that might affect 24 Hr ABPM. |
topic |
Circadian Rhythm Parkinson’s disease non-invasive orthostatic hypotension non-dipping 24 hr ambulatory blood pressure monitoring |
url |
http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00049/full |
work_keys_str_mv |
AT evaestubner 24hrnoninvasiveambulatorybloodpressureandheartratemonitoringinparkinsonsdisease AT ekawatevichayanrat 24hrnoninvasiveambulatorybloodpressureandheartratemonitoringinparkinsonsdisease AT davidelow 24hrnoninvasiveambulatorybloodpressureandheartratemonitoringinparkinsonsdisease AT christopherjmathias 24hrnoninvasiveambulatorybloodpressureandheartratemonitoringinparkinsonsdisease AT stefaneisenmann 24hrnoninvasiveambulatorybloodpressureandheartratemonitoringinparkinsonsdisease AT carlalbrechtehaensch 24hrnoninvasiveambulatorybloodpressureandheartratemonitoringinparkinsonsdisease |
_version_ |
1725662538293575680 |