The Epithelial Circumferential Actin Belt Regulates YAP/TAZ through Nucleocytoplasmic Shuttling of Merlin
Circumferential actin belts underlying the adherens junctions of columnar epithelial cell monolayers control intercellular surface tension and cell shape to maintain tissue integrity. Yes-associated protein (YAP) and its paralog TAZ are proliferation-activating transcriptional coactivators that shut...
Main Authors: | Kana T. Furukawa, Kazunari Yamashita, Natsuki Sakurai, Shigeo Ohno |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-08-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124717309981 |
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