Simultaneous identification of multiple driver pathways in cancer.

Simultaneous identification of multiple driver pathways in cancer.

Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identif...

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Bibliographic Details
Main Authors: Mark D M Leiserson, Dima Blokh, Roded Sharan, Benjamin J Raphael
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23717195/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23717195/pdf/?tool=EBI

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