Eukaryotic Translation Initiation Factor 4AI: A Potential Novel Target in Neuroblastoma

Eukaryotic Translation Initiation Factor 4AI: A Potential Novel Target in Neuroblastoma

Neuroblastoma (NB) is the most common extracranial pediatric solid tumor. Children suffering from high-risk and/or metastatic NB often show no response to therapy, and new therapeutic approaches are urgently needed. Malignant tumor development has been shown to be driven by the dysregulation of euka...

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Bibliographic Details
Main Authors: Christina Skofler, Florian Kleinegger, Stefanie Krassnig, Anna Maria Birkl-Toeglhofer, Georg Singer, Holger Till, Martin Benesch, Regina Cencic, John A. Porco, Jerry Pelletier, Christoph Castellani, Andrea Raicht, Ewa Izycka-Swieszewska, Piotr Czapiewski, Johannes Haybaeck
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
neuroblastoma
eukaryotic initiation factor 4AI (eIF4AI)
rocaglates
CR-1-31-B
SH-SY5Y
Kelly
Online Access:https://www.mdpi.com/2073-4409/10/2/301

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