Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification
<b>AIM:</b> To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure (IOP) after cataract surgery.<b>METHODS:</b>The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation. Patients scheduled for...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874527/ |
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doaj-18fe9779bf924d5dac20bdd051247ef32020-11-25T01:44:28ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982013-12-016685185410.3980/j.issn.2222-3959.2013.06.19Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsificationKemal Örnek0Nesrin Büyüktortop1Nurgül Örnek2Reyhan Oğurel3İnci Elif Erbahçeci4Zafer Onaran5Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.<b>AIM:</b> To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure (IOP) after cataract surgery.<b>METHODS:</b>The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation. Patients scheduled for phacoemulsification were assigned to 1 of 2 groups. The treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery, and the control group received no treatment. The IOP was measured preoperatively and at 2h and 24h postoperatively.<b>RESULTS:</b> The mean IOP change was lower in the treatment group than in the control group at 2h postoperatively. The difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically significant. Twenty-four hours after the surgery, the mean IOP change was still higher in the control group when compared to the treatment group.<b>CONCLUSION:</b> The fixed combination brinzolamide-timolol can effectively reduce IOP after cataract surgery.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874527/brinzolamidetimololcataract surgerycataract surgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kemal Örnek Nesrin Büyüktortop Nurgül Örnek Reyhan Oğurel İnci Elif Erbahçeci Zafer Onaran |
spellingShingle |
Kemal Örnek Nesrin Büyüktortop Nurgül Örnek Reyhan Oğurel İnci Elif Erbahçeci Zafer Onaran Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification International Journal of Ophthalmology brinzolamide timolol cataract surgery cataract surgery |
author_facet |
Kemal Örnek Nesrin Büyüktortop Nurgül Örnek Reyhan Oğurel İnci Elif Erbahçeci Zafer Onaran |
author_sort |
Kemal Örnek |
title |
Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification |
title_short |
Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification |
title_full |
Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification |
title_fullStr |
Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification |
title_full_unstemmed |
Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification |
title_sort |
effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2013-12-01 |
description |
<b>AIM:</b> To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure (IOP) after cataract surgery.<b>METHODS:</b>The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation. Patients scheduled for phacoemulsification were assigned to 1 of 2 groups. The treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery, and the control group received no treatment. The IOP was measured preoperatively and at 2h and 24h postoperatively.<b>RESULTS:</b> The mean IOP change was lower in the treatment group than in the control group at 2h postoperatively. The difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically significant. Twenty-four hours after the surgery, the mean IOP change was still higher in the control group when compared to the treatment group.<b>CONCLUSION:</b> The fixed combination brinzolamide-timolol can effectively reduce IOP after cataract surgery. |
topic |
brinzolamide timolol cataract surgery cataract surgery |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874527/ |
work_keys_str_mv |
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