A novel A792D mutation in the CSF1R gene causes hereditary diffuse leukoencephalopathy with axonal spheroids characterized by slow progression
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an autosomal dominant white matter disease that causes adult-onset cognitive impairment. The clinical manifestations are a variable combination of personality and behavioral changes, cognitive decline, parkinsonism, spasticity, and epil...
Main Authors: | Sakiho Ueda, Hirofumi Yamashita, Ryota Hikiami, Nobukatsu Sawamoto, Kunihiro Yoshida, Ryosuke Takahashi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-03-01
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Series: | eNeurologicalSci |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650215000040 |
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