Apoptosis in the Pancreatic Cancer Tumor Microenvironment—The Double-Edged Sword of Cancer-Associated Fibroblasts

Pancreatic ductal adenocarcinoma (PDAC) is associated with poor prognosis. This is attributed to the disease already being advanced at presentation and having a particularly aggressive tumor biology. The PDAC tumor microenvironment (TME) is characterized by a dense desmoplastic stroma, dominated by...

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Bibliographic Details
Main Authors: Ester Pfeifer, Joy M. Burchell, Francesco Dazzi, Debashis Sarker, Richard Beatson
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
CAF
TME
Online Access:https://www.mdpi.com/2073-4409/10/7/1653