Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation

Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation

BACKGROUND: Liver transplantation (LT) offers a possible cure for patients with hepatocellular carcinoma (HCC) and cirrhosis. However, tumour progression while on the waiting list and tumour recurrence after LT are common. The prognostic significance of various pre- and postoperative variables were...

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Main Authors: Kathy Han, George N Tzimas, Jeffrey S Barkun, Peter Metrakos, Jean I Tchervenkov, Nir Hilzenrat, Phil Wong, M Deschênes
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2007/206383
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spelling doaj-1946c4085610454dbbe641f9b34fd0322020-11-25T00:02:27ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79002007-01-01211394510.1155/2007/206383Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver TransplantationKathy Han0George N Tzimas1Jeffrey S Barkun2Peter Metrakos3Jean I Tchervenkov4Nir Hilzenrat5Phil Wong6M Deschênes7Liver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaBACKGROUND: Liver transplantation (LT) offers a possible cure for patients with hepatocellular carcinoma (HCC) and cirrhosis. However, tumour progression while on the waiting list and tumour recurrence after LT are common. The prognostic significance of various pre- and postoperative variables were investigated in regard to tumour recurrence, with an emphasis on the slope of preoperative serum alpha-fetoprotein (AFP) levels.http://dx.doi.org/10.1155/2007/206383
collection DOAJ
language English
format Article
sources DOAJ
author Kathy Han
George N Tzimas
Jeffrey S Barkun
Peter Metrakos
Jean I Tchervenkov
Nir Hilzenrat
Phil Wong
M Deschênes
spellingShingle Kathy Han
George N Tzimas
Jeffrey S Barkun
Peter Metrakos
Jean I Tchervenkov
Nir Hilzenrat
Phil Wong
M Deschênes
Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
Canadian Journal of Gastroenterology
author_facet Kathy Han
George N Tzimas
Jeffrey S Barkun
Peter Metrakos
Jean I Tchervenkov
Nir Hilzenrat
Phil Wong
M Deschênes
author_sort Kathy Han
title Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_short Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_full Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_fullStr Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_full_unstemmed Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_sort preoperative alpha-fetoprotein slope is predictive of hepatocellular carcinoma recurrence after liver transplantation
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 2007-01-01
description BACKGROUND: Liver transplantation (LT) offers a possible cure for patients with hepatocellular carcinoma (HCC) and cirrhosis. However, tumour progression while on the waiting list and tumour recurrence after LT are common. The prognostic significance of various pre- and postoperative variables were investigated in regard to tumour recurrence, with an emphasis on the slope of preoperative serum alpha-fetoprotein (AFP) levels.
url http://dx.doi.org/10.1155/2007/206383
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AT georgentzimas preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
AT jeffreysbarkun preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
AT petermetrakos preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
AT jeanitchervenkov preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
AT nirhilzenrat preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
AT philwong preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
AT mdeschenes preoperativealphafetoproteinslopeispredictiveofhepatocellularcarcinomarecurrenceafterlivertransplantation
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