Stargazin Dephosphorylation Mediates Homeostatic Synaptic Downscaling of Excitatory Synapses

Stargazin Dephosphorylation Mediates Homeostatic Synaptic Downscaling of Excitatory Synapses

Synaptic scaling is a form of homeostatic plasticity that is critical for maintaining neuronal activity within a dynamic range, and which alters synaptic strength through changes in postsynaptic AMPA-type glutamate receptors. Homeostatic scaling down of excitatory synapses has been shown to occur du...

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Bibliographic Details
Main Authors: Susana R. Louros, Gladys L. Caldeira, Ana Luísa Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
homeostatic plasticity
stargazin
AMPA receptors
synaptic downscaling
membrane trafficking
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00328/full

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