Controlling parasympathetic regulation of heart rate: a gatekeeperrole for RGS proteins in the sinoatrial node

Neurotransmitters released from sympathetic and parasympathetic nerve terminals in the SAN exert their effects via G-protein-coupled receptors. Integration of these different G-protein signals within pacemaker cells of the sinoatrial node (SAN) is critical for proper regulation of heart rate and fu...

Full description

Bibliographic Details
Main Authors: Alexandra eMighiu, Scott Patrick Heximer
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00204/full