Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases
Abstract Objective: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). Materials and Methods: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age...
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doaj-1952beb03c2f4899a2d01aa0876f809b2020-11-24T23:39:24ZengColégio Brasileiro de Radiologia e Diagnóstico por ImagemRadiologia Brasileira1678-7099010.1590/0100-3984.2016-0123S0100-39842017005011102Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 casesLuciana Camara BelémCarolina A. SouzaArthur Soares Souza Jr.Dante Luiz EscuissatoBruno HochheggerLuiz Felipe NobreRosana Souza RodriguesAntônio Carlos Portugal GomesClaudio S. SilvaMarcos Duarte GuimarãesGláucia ZanettiEdson MarchioriAbstract Objective: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). Materials and Methods: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89) years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were centrilobular ground-glass nodules (n = 14; 60.9%), consolidation with high attenuation (n = 10; 43.5%), small dense nodules (n = 9; 39.1%), peripheral reticular opacities associated with small calcified nodules (n = 5; 21.7%), and ground-glass opacities without centrilobular ground-glass nodular opacity (n = 5; 21.7%). Vascular calcification within the chest wall was found in four cases and pleural effusion was observed in five cases. The abnormalities were bilateral in 21 cases. Conclusion: MPC manifested with three main patterns on HRCT, most commonly centrilobular ground-glass nodules, often containing calcifications, followed by dense consolidation and small solid nodules, most of which were calcified. We also described another pattern of peripheral reticular opacities associated with small calcified nodules. These findings should suggest the diagnosis of MPC in the setting of hypercalcemia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017005011102&lng=en&tlng=enCalcificação pulmonar metastáticaTomografia computadorizadaDoenças metabólicasDoenças pulmonares |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Luciana Camara Belém Carolina A. Souza Arthur Soares Souza Jr. Dante Luiz Escuissato Bruno Hochhegger Luiz Felipe Nobre Rosana Souza Rodrigues Antônio Carlos Portugal Gomes Claudio S. Silva Marcos Duarte Guimarães Gláucia Zanetti Edson Marchiori |
spellingShingle |
Luciana Camara Belém Carolina A. Souza Arthur Soares Souza Jr. Dante Luiz Escuissato Bruno Hochhegger Luiz Felipe Nobre Rosana Souza Rodrigues Antônio Carlos Portugal Gomes Claudio S. Silva Marcos Duarte Guimarães Gláucia Zanetti Edson Marchiori Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases Radiologia Brasileira Calcificação pulmonar metastática Tomografia computadorizada Doenças metabólicas Doenças pulmonares |
author_facet |
Luciana Camara Belém Carolina A. Souza Arthur Soares Souza Jr. Dante Luiz Escuissato Bruno Hochhegger Luiz Felipe Nobre Rosana Souza Rodrigues Antônio Carlos Portugal Gomes Claudio S. Silva Marcos Duarte Guimarães Gláucia Zanetti Edson Marchiori |
author_sort |
Luciana Camara Belém |
title |
Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases |
title_short |
Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases |
title_full |
Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases |
title_fullStr |
Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases |
title_full_unstemmed |
Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases |
title_sort |
metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases |
publisher |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
series |
Radiologia Brasileira |
issn |
1678-7099 |
description |
Abstract Objective: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). Materials and Methods: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89) years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were centrilobular ground-glass nodules (n = 14; 60.9%), consolidation with high attenuation (n = 10; 43.5%), small dense nodules (n = 9; 39.1%), peripheral reticular opacities associated with small calcified nodules (n = 5; 21.7%), and ground-glass opacities without centrilobular ground-glass nodular opacity (n = 5; 21.7%). Vascular calcification within the chest wall was found in four cases and pleural effusion was observed in five cases. The abnormalities were bilateral in 21 cases. Conclusion: MPC manifested with three main patterns on HRCT, most commonly centrilobular ground-glass nodules, often containing calcifications, followed by dense consolidation and small solid nodules, most of which were calcified. We also described another pattern of peripheral reticular opacities associated with small calcified nodules. These findings should suggest the diagnosis of MPC in the setting of hypercalcemia. |
topic |
Calcificação pulmonar metastática Tomografia computadorizada Doenças metabólicas Doenças pulmonares |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842017005011102&lng=en&tlng=en |
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