Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the bio...
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doaj-195c368a631848399795537d9ee9cf872021-07-26T14:51:00ZengTaylor & Francis GroupNanocomposites2055-03322021-01-01719710810.1080/20550324.2021.19482421948242Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detectionIsa Anshori0Lavita Nuraviana Rizalputri1Raih Rona Althof2Steven Sean Surjadi3Suksmandhira Harimurti4Gilang Gumilar5Brian Yuliarto6Murni Handayani7Lab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of TechnologyLab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of TechnologyLab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of TechnologyLab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of TechnologyLab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of TechnologyAdvanced Functional Materials Laboratory, Engineering Physics Department, Bandung Institute of TechnologyResearch Center for Nanosciences and Nanotechnology (RCNN), Bandung Institute of TechnologyResearch Center for Metallurgy and Materials, Indonesian Institute of Sciences (LIPI)Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA.http://dx.doi.org/10.1080/20550324.2021.1948242dopaminemulti-walled carbon nanotubesilver nanoparticleelectrochemical biosensornon-enzymatic |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Isa Anshori Lavita Nuraviana Rizalputri Raih Rona Althof Steven Sean Surjadi Suksmandhira Harimurti Gilang Gumilar Brian Yuliarto Murni Handayani |
spellingShingle |
Isa Anshori Lavita Nuraviana Rizalputri Raih Rona Althof Steven Sean Surjadi Suksmandhira Harimurti Gilang Gumilar Brian Yuliarto Murni Handayani Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection Nanocomposites dopamine multi-walled carbon nanotube silver nanoparticle electrochemical biosensor non-enzymatic |
author_facet |
Isa Anshori Lavita Nuraviana Rizalputri Raih Rona Althof Steven Sean Surjadi Suksmandhira Harimurti Gilang Gumilar Brian Yuliarto Murni Handayani |
author_sort |
Isa Anshori |
title |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_short |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_full |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_fullStr |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_full_unstemmed |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_sort |
functionalized multi-walled carbon nanotube/silver nanoparticle (f-mwcnt/agnp) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
publisher |
Taylor & Francis Group |
series |
Nanocomposites |
issn |
2055-0332 |
publishDate |
2021-01-01 |
description |
Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA. |
topic |
dopamine multi-walled carbon nanotube silver nanoparticle electrochemical biosensor non-enzymatic |
url |
http://dx.doi.org/10.1080/20550324.2021.1948242 |
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