Bronchial asthma: new prospects in therapy
The article reviews original and literature data on the use of monoclonal antibodies (MAB) for treatment of patients with severe bronchial asthma (BA), methods of MAB obtaining. Biomolecule targets in BA are some immunoglobulins, CD4 lymphosytes and TNFalpha. Successful use of monoclonal anti-IgE an...
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"Consilium Medicum" Publishing house
2012-03-01
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Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30982 |
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doaj-195f4dee12ad44d5a55374e0aebba2572020-11-25T03:04:44Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422012-03-0184351127998Bronchial asthma: new prospects in therapyA G Chuchalin0Research Institute of PulmonologyThe article reviews original and literature data on the use of monoclonal antibodies (MAB) for treatment of patients with severe bronchial asthma (BA), methods of MAB obtaining. Biomolecule targets in BA are some immunoglobulins, CD4 lymphosytes and TNFalpha. Successful use of monoclonal anti-IgE antibodies in BA by Russian clinicians in 1980s and current experience with administration of foreign MAB drugs (omalizumab, mepolizumab, infliximab, etc.) are considered.https://ter-arkhiv.ru/0040-3660/article/view/30982bronchial asthmatreatmentmonoclonal antibodiesrecombinant bioengineeringomalizumab |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
A G Chuchalin |
spellingShingle |
A G Chuchalin Bronchial asthma: new prospects in therapy Терапевтический архив bronchial asthma treatment monoclonal antibodies recombinant bioengineering omalizumab |
author_facet |
A G Chuchalin |
author_sort |
A G Chuchalin |
title |
Bronchial asthma: new prospects in therapy |
title_short |
Bronchial asthma: new prospects in therapy |
title_full |
Bronchial asthma: new prospects in therapy |
title_fullStr |
Bronchial asthma: new prospects in therapy |
title_full_unstemmed |
Bronchial asthma: new prospects in therapy |
title_sort |
bronchial asthma: new prospects in therapy |
publisher |
"Consilium Medicum" Publishing house |
series |
Терапевтический архив |
issn |
0040-3660 2309-5342 |
publishDate |
2012-03-01 |
description |
The article reviews original and literature data on the use of monoclonal antibodies (MAB) for treatment of patients with severe bronchial asthma (BA), methods of MAB obtaining. Biomolecule targets in BA are some immunoglobulins, CD4 lymphosytes and TNFalpha. Successful use of monoclonal anti-IgE antibodies in BA by Russian clinicians in 1980s and current experience with administration of foreign MAB drugs (omalizumab, mepolizumab, infliximab, etc.) are considered. |
topic |
bronchial asthma treatment monoclonal antibodies recombinant bioengineering omalizumab |
url |
https://ter-arkhiv.ru/0040-3660/article/view/30982 |
work_keys_str_mv |
AT agchuchalin bronchialasthmanewprospectsintherapy |
_version_ |
1724680031175704576 |