Bronchial asthma: new prospects in therapy

The article reviews original and literature data on the use of monoclonal antibodies (MAB) for treatment of patients with severe bronchial asthma (BA), methods of MAB obtaining. Biomolecule targets in BA are some immunoglobulins, CD4 lymphosytes and TNFalpha. Successful use of monoclonal anti-IgE an...

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Main Author: A G Chuchalin
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2012-03-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30982
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spelling doaj-195f4dee12ad44d5a55374e0aebba2572020-11-25T03:04:44Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422012-03-0184351127998Bronchial asthma: new prospects in therapyA G Chuchalin0Research Institute of PulmonologyThe article reviews original and literature data on the use of monoclonal antibodies (MAB) for treatment of patients with severe bronchial asthma (BA), methods of MAB obtaining. Biomolecule targets in BA are some immunoglobulins, CD4 lymphosytes and TNFalpha. Successful use of monoclonal anti-IgE antibodies in BA by Russian clinicians in 1980s and current experience with administration of foreign MAB drugs (omalizumab, mepolizumab, infliximab, etc.) are considered.https://ter-arkhiv.ru/0040-3660/article/view/30982bronchial asthmatreatmentmonoclonal antibodiesrecombinant bioengineeringomalizumab
collection DOAJ
language Russian
format Article
sources DOAJ
author A G Chuchalin
spellingShingle A G Chuchalin
Bronchial asthma: new prospects in therapy
Терапевтический архив
bronchial asthma
treatment
monoclonal antibodies
recombinant bioengineering
omalizumab
author_facet A G Chuchalin
author_sort A G Chuchalin
title Bronchial asthma: new prospects in therapy
title_short Bronchial asthma: new prospects in therapy
title_full Bronchial asthma: new prospects in therapy
title_fullStr Bronchial asthma: new prospects in therapy
title_full_unstemmed Bronchial asthma: new prospects in therapy
title_sort bronchial asthma: new prospects in therapy
publisher "Consilium Medicum" Publishing house
series Терапевтический архив
issn 0040-3660
2309-5342
publishDate 2012-03-01
description The article reviews original and literature data on the use of monoclonal antibodies (MAB) for treatment of patients with severe bronchial asthma (BA), methods of MAB obtaining. Biomolecule targets in BA are some immunoglobulins, CD4 lymphosytes and TNFalpha. Successful use of monoclonal anti-IgE antibodies in BA by Russian clinicians in 1980s and current experience with administration of foreign MAB drugs (omalizumab, mepolizumab, infliximab, etc.) are considered.
topic bronchial asthma
treatment
monoclonal antibodies
recombinant bioengineering
omalizumab
url https://ter-arkhiv.ru/0040-3660/article/view/30982
work_keys_str_mv AT agchuchalin bronchialasthmanewprospectsintherapy
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