Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

Nonalcoholic fatty liver disease (NAFLD) is characterized by the development of steatosis, which can ultimately compromise liver function. Mitochondria are key players in obesity-induced metabolic disorders; however, the distinct role of hypercaloric diet constituents in hepatic cellular oxidative s...

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Bibliographic Details
Main Authors: Ines C. M. Simoes, Agnieszka Karkucinska-Wieckowska, Justyna Janikiewicz, Sylwia Szymanska, Maciej Pronicki, Pawel Dobrzyn, Michal Dabrowski, Agnieszka Dobrzyn, Paulo J. Oliveira, Hans Zischka, Yaiza Potes, Mariusz R. Wieckowski
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antioxidants
Subjects:
mitochondria
oxidative stress
peroxisomes
autophagy
steatosis
Online Access:https://www.mdpi.com/2076-3921/9/10/995

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