Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study
Summary: Objective: To determine the epidemiology of the nasal carriage of Staphylococcus aureus and its susceptibility pattern among preclinical medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University. Methods: Nasal swabs were taken from 128 preclin...
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doaj-199cee4eccd347339ce22da6d89c86ff2020-11-24T21:39:01ZengElsevierJournal of Infection and Public Health1876-03412013-06-0163196201Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional studyArucha Treesirichod0Sumalee Hantagool1Olarn Prommalikit2Corresponding author at: Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, HRH Princess Maha Chakri Sirindhorn Medical Center, Rangsit-Nakhonnayok Road, Ongkharak, Nakhonnayok 26120, Thailand. Tel.: +66 815935232.; Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Bangkok, ThailandDepartment of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Bangkok, ThailandDepartment of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Bangkok, ThailandSummary: Objective: To determine the epidemiology of the nasal carriage of Staphylococcus aureus and its susceptibility pattern among preclinical medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University. Methods: Nasal swabs were taken from 128 preclinical medical students prior to working at the hospital. Susceptibility testing of S. aureus was performed using Kirby Bauer's disc diffusion method. Results: Of the 128 participants, 38/128 (29.7%; 95% confidence interval [CI] = 21.8%, 37.6%) were carriers of S. aureus. No methicillin-resistant S. aureus was detected by the cefoxitin disk diffusion test. Resistance of S. aureus to erythromycin, clindamycin, tetracycline, chloramphenicol and fusidic acid was observed at the following rates: 63.2% (95% CI; 47.8%, 78.5%), 63.2% (95% CI; 47.8%, 78.5%), 34.2% (95% CI; 19.1%, 49.3%), 2.6% (95% CI; −2.5%, 7.7%) and 2.6% (95% CI; −2.5%, 7.7%), respectively. There was no statistically significant correlation between nasal carriage of S. aureus and possible risk factors. Conclusions: The prevalence of asymptomatic nasal carriage of S. aureus was higher than reported by previous literature in Thailand, and S. aureus isolates exhibited relatively high resistance to erythromycin and clindamycin. Keywords: Staphylococcus aureus, Medical students, Nasal carriage, Antimicrobial susceptibilityhttp://www.sciencedirect.com/science/article/pii/S1876034113000105 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Arucha Treesirichod Sumalee Hantagool Olarn Prommalikit |
spellingShingle |
Arucha Treesirichod Sumalee Hantagool Olarn Prommalikit Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study Journal of Infection and Public Health |
author_facet |
Arucha Treesirichod Sumalee Hantagool Olarn Prommalikit |
author_sort |
Arucha Treesirichod |
title |
Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study |
title_short |
Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study |
title_full |
Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study |
title_fullStr |
Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study |
title_full_unstemmed |
Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: A cross sectional study |
title_sort |
nasal carriage and antimicrobial susceptibility of staphylococcus aureus among medical students at the hrh princess maha chakri sirindhorn medical center, thailand: a cross sectional study |
publisher |
Elsevier |
series |
Journal of Infection and Public Health |
issn |
1876-0341 |
publishDate |
2013-06-01 |
description |
Summary: Objective: To determine the epidemiology of the nasal carriage of Staphylococcus aureus and its susceptibility pattern among preclinical medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University. Methods: Nasal swabs were taken from 128 preclinical medical students prior to working at the hospital. Susceptibility testing of S. aureus was performed using Kirby Bauer's disc diffusion method. Results: Of the 128 participants, 38/128 (29.7%; 95% confidence interval [CI] = 21.8%, 37.6%) were carriers of S. aureus. No methicillin-resistant S. aureus was detected by the cefoxitin disk diffusion test. Resistance of S. aureus to erythromycin, clindamycin, tetracycline, chloramphenicol and fusidic acid was observed at the following rates: 63.2% (95% CI; 47.8%, 78.5%), 63.2% (95% CI; 47.8%, 78.5%), 34.2% (95% CI; 19.1%, 49.3%), 2.6% (95% CI; −2.5%, 7.7%) and 2.6% (95% CI; −2.5%, 7.7%), respectively. There was no statistically significant correlation between nasal carriage of S. aureus and possible risk factors. Conclusions: The prevalence of asymptomatic nasal carriage of S. aureus was higher than reported by previous literature in Thailand, and S. aureus isolates exhibited relatively high resistance to erythromycin and clindamycin. Keywords: Staphylococcus aureus, Medical students, Nasal carriage, Antimicrobial susceptibility |
url |
http://www.sciencedirect.com/science/article/pii/S1876034113000105 |
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