Emergency Department Visits due to the Bleeding Complication of Warfarin
INTRODUCTION[|]Warfarin is an anticoagulant that is used in case of thromboembolism risk or events as a prophylactic or therapeutic agent. In this study, we investigated the emergency visits due to the bleeding complication of warfarin.[¤]METHODS[|]The patients admitted to emergency department with...
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Turkish Foundation of Family Medicine
2020-04-01
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doaj-199d1245bfa44026826cefb925dd45302020-11-25T01:48:06ZengTurkish Foundation of Family MedicineAnatolian Journal of Family Medicine2651-34552020-04-0131596310.5505/anatoljfm.2019.25743ANATOLJFM-25743Emergency Department Visits due to the Bleeding Complication of WarfarinBahar Gülcay Çat0Umut Yücel Çavuş1Mesut Bakır2Duygu Yılmaz3Sinan Yıldırım4Department of Emergency Medicine, Mersin City Training and Research Hospital, Mersin, TurkeyDepartment of Emergency Medicine, Ankara Training and Research Hospital, Ankara, TurkeyDepartment of Anesthesiology, Division of Algology, Mersin University Faculty of Medicine, Mersin, TurkeyDepartment of Emergency Medicine, Manisa Turgutlu State Hospital, Manisa, TurkeyDepartment of Emergency Medicine, Canakkale State Hospital, Canakkale, TurkeyINTRODUCTION[|]Warfarin is an anticoagulant that is used in case of thromboembolism risk or events as a prophylactic or therapeutic agent. In this study, we investigated the emergency visits due to the bleeding complication of warfarin.[¤]METHODS[|]The patients admitted to emergency department with bleeding and using warfarin were included this study in a three year period. Age, gender, liver and kidney function tests, the time period of the warfarin use and the frequency of the control visits were recoded.[¤]RESULTS[|]The patients admitted to emergency department with bleeding and using warfarin were included this study in a three year period (n=243). The regular follow up of coagulation parameter was observed in 92 (42.8%) patients. One hundred six (43.6%) of the patients had had a bleeding complication before. The most frequently observed bleeding region was urinary system (n=87, 35.8%). The INR level was greater than five in 223 (91.8%) of the patients. Fresh frozen plasma was used 193 (75.3%); prothrombin complex concentration was used in 15 (6.2%) patients; conservative management was preferred in 45(18.5%) patients. Mortality rate was 22 (9.1%) and 97 (39.9%) of the patients were discharged from emergency department without hospitalization. Female gender, low hemoglobin level, abnormal liver and kidney tests, INR level over 10 and irregular INR follow up were associated with both mortality and major bleeding (respectively; p=0.750, p<0.001, p<0.001, p<0.001, p<0.001, p<0.001).[¤]DISCUSSION AND CONCLUSION[|]The interaction with other medications or foods, bleeding complications, its requirement of regular follow up of coagulation parameters and dose adjustment make difficult its use. We should tell the patients the importance of following the INR level regularly, especially in patients with co-morbid diseases.[¤]https://www.journalagent.com/z4/download_fulltext.asp?pdir=anatoljfm&un=ANATOLJFM-25743anticoagulantmortalitywarfarin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bahar Gülcay Çat Umut Yücel Çavuş Mesut Bakır Duygu Yılmaz Sinan Yıldırım |
spellingShingle |
Bahar Gülcay Çat Umut Yücel Çavuş Mesut Bakır Duygu Yılmaz Sinan Yıldırım Emergency Department Visits due to the Bleeding Complication of Warfarin Anatolian Journal of Family Medicine anticoagulant mortality warfarin |
author_facet |
Bahar Gülcay Çat Umut Yücel Çavuş Mesut Bakır Duygu Yılmaz Sinan Yıldırım |
author_sort |
Bahar Gülcay Çat |
title |
Emergency Department Visits due to the Bleeding Complication of Warfarin |
title_short |
Emergency Department Visits due to the Bleeding Complication of Warfarin |
title_full |
Emergency Department Visits due to the Bleeding Complication of Warfarin |
title_fullStr |
Emergency Department Visits due to the Bleeding Complication of Warfarin |
title_full_unstemmed |
Emergency Department Visits due to the Bleeding Complication of Warfarin |
title_sort |
emergency department visits due to the bleeding complication of warfarin |
publisher |
Turkish Foundation of Family Medicine |
series |
Anatolian Journal of Family Medicine |
issn |
2651-3455 |
publishDate |
2020-04-01 |
description |
INTRODUCTION[|]Warfarin is an anticoagulant that is used in case of thromboembolism risk or events as a prophylactic or therapeutic agent. In this study, we investigated the emergency visits due to the bleeding complication of warfarin.[¤]METHODS[|]The patients admitted to emergency department with bleeding and using warfarin were included this study in a three year period. Age, gender, liver and kidney function tests, the time period of the warfarin use and the frequency of the control visits were recoded.[¤]RESULTS[|]The patients admitted to emergency department with bleeding and using warfarin were included this study in a three year period (n=243). The regular follow up of coagulation parameter was observed in 92 (42.8%) patients. One hundred six (43.6%) of the patients had had a bleeding complication before. The most frequently observed bleeding region was urinary system (n=87, 35.8%). The INR level was greater than five in 223 (91.8%) of the patients. Fresh frozen plasma was used 193 (75.3%); prothrombin complex concentration was used in 15 (6.2%) patients; conservative management was preferred in 45(18.5%) patients. Mortality rate was 22 (9.1%) and 97 (39.9%) of the patients were discharged from emergency department without hospitalization. Female gender, low hemoglobin level, abnormal liver and kidney tests, INR level over 10 and irregular INR follow up were associated with both mortality and major bleeding (respectively; p=0.750, p<0.001, p<0.001, p<0.001, p<0.001, p<0.001).[¤]DISCUSSION AND CONCLUSION[|]The interaction with other medications or foods, bleeding complications, its requirement of regular follow up of coagulation parameters and dose adjustment make difficult its use. We should tell the patients the importance of following the INR level regularly, especially in patients with co-morbid diseases.[¤] |
topic |
anticoagulant mortality warfarin |
url |
https://www.journalagent.com/z4/download_fulltext.asp?pdir=anatoljfm&un=ANATOLJFM-25743 |
work_keys_str_mv |
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