Genome-Wide DNA Methylation Patterns of Bovine Blastocysts Developed In Vivo from Embryos Completed Different Stages of Development In Vitro.

Genome-Wide DNA Methylation Patterns of Bovine Blastocysts Developed In Vivo from Embryos Completed Different Stages of Development In Vitro.

Early embryonic loss and altered gene expression in in vitro produced blastocysts are believed to be partly caused by aberrant DNA methylation. However, specific embryonic stage which is sensitive to in vitro culture conditions to alter the DNA methylation profile of the resulting blastocysts remain...

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Bibliographic Details
Main Authors: Dessie Salilew-Wondim, Eric Fournier, Michael Hoelker, Mohammed Saeed-Zidane, Ernst Tholen, Christian Looft, Christiane Neuhoff, Urban Besenfelder, Vita Havlicek, Franca Rings, Dominic Gagné, Marc-André Sirard, Claude Robert, Habib A Shojaei Saadi, Ahmed Gad, Karl Schellander, Dawit Tesfaye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4633222?pdf=render

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