Integrated omics in Drosophila uncover a circadian kinome
Phosphorylation plays an important role in the regulation of molecular circadian clocks. Here the authors utilize multi-omics data from flies to describe the circadian kinome and identify GASKET as a potentially important regulator within the circadian kinase network.
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2020-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16514-z |
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doaj-19eedcd4ad5c462ebc3ad0ecfb73cbaf2021-06-06T11:16:11ZengNature Publishing GroupNature Communications2041-17232020-06-0111111510.1038/s41467-020-16514-zIntegrated omics in Drosophila uncover a circadian kinomeChenwei Wang0Ke Shui1Shanshan Ma2Shaofeng Lin3Ying Zhang4Bo Wen5Wankun Deng6Haodong Xu7Hui Hu8Anyuan Guo9Yu Xue10Luoying Zhang11Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyDepartment of Molecular and Human Genetics, Lester and Sue Smith Breast Center, Baylor College of MedicineKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyPhosphorylation plays an important role in the regulation of molecular circadian clocks. Here the authors utilize multi-omics data from flies to describe the circadian kinome and identify GASKET as a potentially important regulator within the circadian kinase network.https://doi.org/10.1038/s41467-020-16514-z |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chenwei Wang Ke Shui Shanshan Ma Shaofeng Lin Ying Zhang Bo Wen Wankun Deng Haodong Xu Hui Hu Anyuan Guo Yu Xue Luoying Zhang |
spellingShingle |
Chenwei Wang Ke Shui Shanshan Ma Shaofeng Lin Ying Zhang Bo Wen Wankun Deng Haodong Xu Hui Hu Anyuan Guo Yu Xue Luoying Zhang Integrated omics in Drosophila uncover a circadian kinome Nature Communications |
author_facet |
Chenwei Wang Ke Shui Shanshan Ma Shaofeng Lin Ying Zhang Bo Wen Wankun Deng Haodong Xu Hui Hu Anyuan Guo Yu Xue Luoying Zhang |
author_sort |
Chenwei Wang |
title |
Integrated omics in Drosophila uncover a circadian kinome |
title_short |
Integrated omics in Drosophila uncover a circadian kinome |
title_full |
Integrated omics in Drosophila uncover a circadian kinome |
title_fullStr |
Integrated omics in Drosophila uncover a circadian kinome |
title_full_unstemmed |
Integrated omics in Drosophila uncover a circadian kinome |
title_sort |
integrated omics in drosophila uncover a circadian kinome |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2020-06-01 |
description |
Phosphorylation plays an important role in the regulation of molecular circadian clocks. Here the authors utilize multi-omics data from flies to describe the circadian kinome and identify GASKET as a potentially important regulator within the circadian kinase network. |
url |
https://doi.org/10.1038/s41467-020-16514-z |
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