Integrated omics in Drosophila uncover a circadian kinome

Phosphorylation plays an important role in the regulation of molecular circadian clocks. Here the authors utilize multi-omics data from flies to describe the circadian kinome and identify GASKET as a potentially important regulator within the circadian kinase network.

Bibliographic Details
Main Authors:	Chenwei Wang, Ke Shui, Shanshan Ma, Shaofeng Lin, Ying Zhang, Bo Wen, Wankun Deng, Haodong Xu, Hui Hu, Anyuan Guo, Yu Xue, Luoying Zhang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-16514-z

id	doaj-19eedcd4ad5c462ebc3ad0ecfb73cbaf
record_format	Article
spelling	doaj-19eedcd4ad5c462ebc3ad0ecfb73cbaf2021-06-06T11:16:11ZengNature Publishing GroupNature Communications2041-17232020-06-0111111510.1038/s41467-020-16514-zIntegrated omics in Drosophila uncover a circadian kinomeChenwei Wang0Ke Shui1Shanshan Ma2Shaofeng Lin3Ying Zhang4Bo Wen5Wankun Deng6Haodong Xu7Hui Hu8Anyuan Guo9Yu Xue10Luoying Zhang11Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyDepartment of Molecular and Human Genetics, Lester and Sue Smith Breast Center, Baylor College of MedicineKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyKey Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyPhosphorylation plays an important role in the regulation of molecular circadian clocks. Here the authors utilize multi-omics data from flies to describe the circadian kinome and identify GASKET as a potentially important regulator within the circadian kinase network.https://doi.org/10.1038/s41467-020-16514-z
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Chenwei Wang Ke Shui Shanshan Ma Shaofeng Lin Ying Zhang Bo Wen Wankun Deng Haodong Xu Hui Hu Anyuan Guo Yu Xue Luoying Zhang
spellingShingle	Chenwei Wang Ke Shui Shanshan Ma Shaofeng Lin Ying Zhang Bo Wen Wankun Deng Haodong Xu Hui Hu Anyuan Guo Yu Xue Luoying Zhang Integrated omics in Drosophila uncover a circadian kinome Nature Communications
author_facet	Chenwei Wang Ke Shui Shanshan Ma Shaofeng Lin Ying Zhang Bo Wen Wankun Deng Haodong Xu Hui Hu Anyuan Guo Yu Xue Luoying Zhang
author_sort	Chenwei Wang
title	Integrated omics in Drosophila uncover a circadian kinome
title_short	Integrated omics in Drosophila uncover a circadian kinome
title_full	Integrated omics in Drosophila uncover a circadian kinome
title_fullStr	Integrated omics in Drosophila uncover a circadian kinome
title_full_unstemmed	Integrated omics in Drosophila uncover a circadian kinome
title_sort	integrated omics in drosophila uncover a circadian kinome
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-06-01
description	Phosphorylation plays an important role in the regulation of molecular circadian clocks. Here the authors utilize multi-omics data from flies to describe the circadian kinome and identify GASKET as a potentially important regulator within the circadian kinase network.
url	https://doi.org/10.1038/s41467-020-16514-z
work_keys_str_mv	AT chenweiwang integratedomicsindrosophilauncoveracircadiankinome AT keshui integratedomicsindrosophilauncoveracircadiankinome AT shanshanma integratedomicsindrosophilauncoveracircadiankinome AT shaofenglin integratedomicsindrosophilauncoveracircadiankinome AT yingzhang integratedomicsindrosophilauncoveracircadiankinome AT bowen integratedomicsindrosophilauncoveracircadiankinome AT wankundeng integratedomicsindrosophilauncoveracircadiankinome AT haodongxu integratedomicsindrosophilauncoveracircadiankinome AT huihu integratedomicsindrosophilauncoveracircadiankinome AT anyuanguo integratedomicsindrosophilauncoveracircadiankinome AT yuxue integratedomicsindrosophilauncoveracircadiankinome AT luoyingzhang integratedomicsindrosophilauncoveracircadiankinome
_version_	1721394162873401344

Integrated omics in Drosophila uncover a circadian kinome

Similar Items