Role of nitric oxide synthases in early blood-brain barrier disruption following transient focal cerebral ischemia.

Role of nitric oxide synthases in early blood-brain barrier disruption following transient focal cerebral ischemia.

The role of nitric oxide synthases (NOSs) in early blood-brain barrier (BBB) disruption was determined using a new mouse model of transient focal cerebral ischemia. Ischemia was induced by ligating the middle cerebral artery (MCA) at its M2 segment and reperfusion was induced by releasing the ligati...

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Bibliographic Details
Main Authors: Zheng Jiang, Chun Li, Denise M Arrick, Shu Yang, Alexandra E Baluna, Hong Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3966853?pdf=render

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