Microgravity simulation activates Cdc42 via Rap1GDS1 to promote vascular branch morphogenesis during vasculogenesis

Microgravity simulation activates Cdc42 via Rap1GDS1 to promote vascular branch morphogenesis during vasculogenesis

Gravity plays an important role in normal tissue maintenance. The ability of stem cells to repair tissue loss in space through regeneration and differentiation remains largely unknown. To investigate the impact of microgravity on blood vessel formation from pluripotent stem cells, we employed the em...

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Bibliographic Details
Main Authors: Shouli Wang, Zhao Yin, Bei Zhao, Yanmei Qi, Jie Liu, Saum A. Rahimi, Leonard Y. Lee, Shaohua Li
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Research
Subjects:
Embryonic stem cells
Vasculogenesis
Rho GTPases
Rap1GDS1
Microgravity
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302325

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