Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension

Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension

<p>Abstract</p> <p>Background</p> <p>Endothelin-1 (ET-1) and Nitric Oxide (NO) are crucial mediators for establishing pulmonary artery hypertension (PAH). We tested the hypothesis that their imbalance might also occur in COPD patients with PAH.</p> <p>Method...

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Bibliographic Details
Main Authors: Dragonieri Silvano, Cardone Rosa, Gadaleta Felice, Di Gioia Giuseppe, Seccia Teresa, Maniscalco Mauro, Scoditti Cristina, Carratu Pierluigi, Pierucci Paola, Spanevello Antonio, Resta Onofrio
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Pulmonary Medicine
Online Access:http://www.biomedcentral.com/1471-2466/8/20

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