Characterization of lens based photoacoustic imaging system
Some of the challenges in translating photoacoustic (PA) imaging to clinical applications includes limited view of the target tissue, low signal to noise ratio and the high cost of developing real-time systems. Acoustic lens based PA imaging systems, also known as PA cameras are a potential alternat...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-12-01
|
Series: | Photoacoustics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213597917300216 |
id |
doaj-1a4850b801df4d2e9eb2badd78869f53 |
---|---|
record_format |
Article |
spelling |
doaj-1a4850b801df4d2e9eb2badd78869f532020-11-25T02:36:42ZengElsevierPhotoacoustics2213-59792017-12-018C374710.1016/j.pacs.2017.09.003Characterization of lens based photoacoustic imaging systemKalloor Joseph Francis0Bhargava Chinni1Sumohana S. Channappayya2Rajalakshmi Pachamuthu3Vikram S. Dogra4Navalgund Rao5Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, IndiaDepartment of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USADepartment of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, IndiaDepartment of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, IndiaDepartment of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USAChester F. Carlson Center for Imaging Science, Rochester Institute of Technology, 54 Lomb Memorial Drive, Rochester, NY 14623, USASome of the challenges in translating photoacoustic (PA) imaging to clinical applications includes limited view of the target tissue, low signal to noise ratio and the high cost of developing real-time systems. Acoustic lens based PA imaging systems, also known as PA cameras are a potential alternative to conventional imaging systems in these scenarios. The 3D focusing action of lens enables real-time C-scan imaging with a 2D transducer array. In this paper, we model the underlying physics in a PA camera in the mathematical framework of an imaging system and derive a closed form expression for the point spread function (PSF). Experimental verification follows including the details on how to design and fabricate the lens inexpensively. The system PSF is evaluated over a 3D volume that can be imaged by this PA camera. Its utility is demonstrated by imaging phantom and an ex vivo human prostate tissue sample.http://www.sciencedirect.com/science/article/pii/S2213597917300216Acoustic lensPhotoacoustic cameraPoint spread functionResolutionEx vivo imaging |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kalloor Joseph Francis Bhargava Chinni Sumohana S. Channappayya Rajalakshmi Pachamuthu Vikram S. Dogra Navalgund Rao |
spellingShingle |
Kalloor Joseph Francis Bhargava Chinni Sumohana S. Channappayya Rajalakshmi Pachamuthu Vikram S. Dogra Navalgund Rao Characterization of lens based photoacoustic imaging system Photoacoustics Acoustic lens Photoacoustic camera Point spread function Resolution Ex vivo imaging |
author_facet |
Kalloor Joseph Francis Bhargava Chinni Sumohana S. Channappayya Rajalakshmi Pachamuthu Vikram S. Dogra Navalgund Rao |
author_sort |
Kalloor Joseph Francis |
title |
Characterization of lens based photoacoustic imaging system |
title_short |
Characterization of lens based photoacoustic imaging system |
title_full |
Characterization of lens based photoacoustic imaging system |
title_fullStr |
Characterization of lens based photoacoustic imaging system |
title_full_unstemmed |
Characterization of lens based photoacoustic imaging system |
title_sort |
characterization of lens based photoacoustic imaging system |
publisher |
Elsevier |
series |
Photoacoustics |
issn |
2213-5979 |
publishDate |
2017-12-01 |
description |
Some of the challenges in translating photoacoustic (PA) imaging to clinical applications includes limited view of the target tissue, low signal to noise ratio and the high cost of developing real-time systems. Acoustic lens based PA imaging systems, also known as PA cameras are a potential alternative to conventional imaging systems in these scenarios. The 3D focusing action of lens enables real-time C-scan imaging with a 2D transducer array. In this paper, we model the underlying physics in a PA camera in the mathematical framework of an imaging system and derive a closed form expression for the point spread function (PSF). Experimental verification follows including the details on how to design and fabricate the lens inexpensively. The system PSF is evaluated over a 3D volume that can be imaged by this PA camera. Its utility is demonstrated by imaging phantom and an ex vivo human prostate tissue sample. |
topic |
Acoustic lens Photoacoustic camera Point spread function Resolution Ex vivo imaging |
url |
http://www.sciencedirect.com/science/article/pii/S2213597917300216 |
work_keys_str_mv |
AT kalloorjosephfrancis characterizationoflensbasedphotoacousticimagingsystem AT bhargavachinni characterizationoflensbasedphotoacousticimagingsystem AT sumohanaschannappayya characterizationoflensbasedphotoacousticimagingsystem AT rajalakshmipachamuthu characterizationoflensbasedphotoacousticimagingsystem AT vikramsdogra characterizationoflensbasedphotoacousticimagingsystem AT navalgundrao characterizationoflensbasedphotoacousticimagingsystem |
_version_ |
1724798504265580544 |