Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique
OBJECTIVE To analyze the prevalence of IgG antibodies to Toxoplasma gondii in patients infected with HIV/AIDS and the association of demographic and social variables. METHODS Descriptive cross-sectional study that included the analysis of sociodemographic data and laboratory findings of 200 patien...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2013-10-01
|
Series: | Revista de Saúde Pública |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102013000500890&lng=en&tlng=en |
id |
doaj-1a544ff1102d4bbeb59dbd11b4c45d75 |
---|---|
record_format |
Article |
spelling |
doaj-1a544ff1102d4bbeb59dbd11b4c45d752020-11-25T01:04:21ZengUniversidade de São PauloRevista de Saúde Pública1518-87872013-10-0147589089610.1590/S0034-8910.2013047004661S0034-89102013000500890Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, MozambiqueAbílio DomingosLucy Sayuri ItoElizabeth CoelhoJorge Manuel LúcioLuiza Harunari MatidaAlberto Novaes Ramos JrOBJECTIVE To analyze the prevalence of IgG antibodies to Toxoplasma gondii in patients infected with HIV/AIDS and the association of demographic and social variables. METHODS Descriptive cross-sectional study that included the analysis of sociodemographic data and laboratory findings of 200 patients infected with HIV/AIDS treated in a laboratory unit in Maputo, Mozambique, in 2010. Individual data for all participants were collected with a self-administered questionnaire. Plasma samples were tested for IgG testing of anti- T. gondii using hemagglutination for the analysis of antibodies. RESULTS The seroprevalence of IgG anti- T. gondii was 46.0% (95%CI 39.2;52.9), 39.3% (95%CI 29.5;50.0) in men and 50.9% (95%CI 41.9;59.8) in women, with no difference between sex (OR 1.30; 95%CI 0.95;1.77; p = 0.12). Ages ranged from 10 to 60 years, with a higher prevalence of infection in older age groups, but with no significant difference between them. Regularly consuming cattle meat (OR 1.74; 95%CI 1.04;2.89, p = 0.05), breeding cats/dogs (OR 6.18; 95%CI 3.60;10.62, p < 0.000) and having regular contact with soil (OR 3.38; 95%CI 2.19;5.21; p < 0.000) were significantly associated with risk of latent infection. CONCLUSIONS Toxoplasmosis is an infection with high prevalence in Mozambique. Cultural and behavioral aspects increase the risk. Toxoplasmosis can be responsible in our environment by the great burden of morbidity and mortality associated with meningoencephalic injuries in patients with HIV/AIDS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102013000500890&lng=en&tlng=enToxoplasmosis, epidemiologíaInfecciones Oportunistas Relacionadas con el SIDAInfecciones por VIH, epidemiologíaEstudios Seroepidemiológicos |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abílio Domingos Lucy Sayuri Ito Elizabeth Coelho Jorge Manuel Lúcio Luiza Harunari Matida Alberto Novaes Ramos Jr |
spellingShingle |
Abílio Domingos Lucy Sayuri Ito Elizabeth Coelho Jorge Manuel Lúcio Luiza Harunari Matida Alberto Novaes Ramos Jr Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique Revista de Saúde Pública Toxoplasmosis, epidemiología Infecciones Oportunistas Relacionadas con el SIDA Infecciones por VIH, epidemiología Estudios Seroepidemiológicos |
author_facet |
Abílio Domingos Lucy Sayuri Ito Elizabeth Coelho Jorge Manuel Lúcio Luiza Harunari Matida Alberto Novaes Ramos Jr |
author_sort |
Abílio Domingos |
title |
Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique |
title_short |
Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique |
title_full |
Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique |
title_fullStr |
Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique |
title_full_unstemmed |
Seroprevalence of Toxoplasma gondii IgG antibody in HIV/AIDS-infected individuals in Maputo, Mozambique |
title_sort |
seroprevalence of toxoplasma gondii igg antibody in hiv/aids-infected individuals in maputo, mozambique |
publisher |
Universidade de São Paulo |
series |
Revista de Saúde Pública |
issn |
1518-8787 |
publishDate |
2013-10-01 |
description |
OBJECTIVE To analyze the prevalence of IgG antibodies to Toxoplasma gondii in patients infected with HIV/AIDS and the association of demographic and social variables. METHODS Descriptive cross-sectional study that included the analysis of sociodemographic data and laboratory findings of 200 patients infected with HIV/AIDS treated in a laboratory unit in Maputo, Mozambique, in 2010. Individual data for all participants were collected with a self-administered questionnaire. Plasma samples were tested for IgG testing of anti- T. gondii using hemagglutination for the analysis of antibodies. RESULTS The seroprevalence of IgG anti- T. gondii was 46.0% (95%CI 39.2;52.9), 39.3% (95%CI 29.5;50.0) in men and 50.9% (95%CI 41.9;59.8) in women, with no difference between sex (OR 1.30; 95%CI 0.95;1.77; p = 0.12). Ages ranged from 10 to 60 years, with a higher prevalence of infection in older age groups, but with no significant difference between them. Regularly consuming cattle meat (OR 1.74; 95%CI 1.04;2.89, p = 0.05), breeding cats/dogs (OR 6.18; 95%CI 3.60;10.62, p < 0.000) and having regular contact with soil (OR 3.38; 95%CI 2.19;5.21; p < 0.000) were significantly associated with risk of latent infection. CONCLUSIONS Toxoplasmosis is an infection with high prevalence in Mozambique. Cultural and behavioral aspects increase the risk. Toxoplasmosis can be responsible in our environment by the great burden of morbidity and mortality associated with meningoencephalic injuries in patients with HIV/AIDS. |
topic |
Toxoplasmosis, epidemiología Infecciones Oportunistas Relacionadas con el SIDA Infecciones por VIH, epidemiología Estudios Seroepidemiológicos |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102013000500890&lng=en&tlng=en |
work_keys_str_mv |
AT abiliodomingos seroprevalenceoftoxoplasmagondiiiggantibodyinhivaidsinfectedindividualsinmaputomozambique AT lucysayuriito seroprevalenceoftoxoplasmagondiiiggantibodyinhivaidsinfectedindividualsinmaputomozambique AT elizabethcoelho seroprevalenceoftoxoplasmagondiiiggantibodyinhivaidsinfectedindividualsinmaputomozambique AT jorgemanuellucio seroprevalenceoftoxoplasmagondiiiggantibodyinhivaidsinfectedindividualsinmaputomozambique AT luizaharunarimatida seroprevalenceoftoxoplasmagondiiiggantibodyinhivaidsinfectedindividualsinmaputomozambique AT albertonovaesramosjr seroprevalenceoftoxoplasmagondiiiggantibodyinhivaidsinfectedindividualsinmaputomozambique |
_version_ |
1725198687244648448 |