Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger
Feline parvovirus (FPV) is a small, non-enveloped, single-stranded DNA virus that infects cats. We recently isolated a feline parvovirus Fe–P2 strain from a dead stray cat in Iksan, 2017. Its partial genomic sequence (4,643 bases) was obtained, and phylogenetic analysis based on the VP2 nucleotide s...
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doaj-1a568a452252416a917c6da8f5f6c3342021-05-07T10:31:56ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-05-01810.3389/fvets.2021.650866650866Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian BadgerYoung Ji Kim0Young Ji Kim1Sun-Woo Yoon2Sun-Woo Yoon3Jin Ho Jang4Jin Ho Jang5Dae Gwin Jeong6Dae Gwin Jeong7Beom Jun Lee8Hye Kwon Kim9Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South KoreaCollege of Veterinary Medicine, Chungbuk National University, Chungju, South KoreaInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South KoreaCollege of Bioscience, University of Science and Technology, Daejeon, South KoreaDepartment of Wildlife Disease, College of Veterinary Science, Jeju National University, Jeju, South KoreaChungnam Wild Animal Rescue Center, Kongju National University, Yesan, South KoreaInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South KoreaCollege of Bioscience, University of Science and Technology, Daejeon, South KoreaCollege of Veterinary Medicine, Chungbuk National University, Chungju, South KoreaDepartment of Microbiology, College of Natural Science, Chungbuk National University, Cheongju, South KoreaFeline parvovirus (FPV) is a small, non-enveloped, single-stranded DNA virus that infects cats. We recently isolated a feline parvovirus Fe–P2 strain from a dead stray cat in Iksan, 2017. Its partial genomic sequence (4,643 bases) was obtained, and phylogenetic analysis based on the VP2 nucleotide sequence showed that the FPV Fe-P2 strain was closely related to the FPV isolate Gigucheon in cat, 2017 (MN400978). In addition, we performed a serum neutralization (SN) test with the FPV isolates in various mammalian sera. These were from raccoon dog, water deer, Eurasian otter, Korean hare, leopard cat, and Asian badger, which were kindly provided by Chungnam Wild Animal Rescue Center. Notably, serological evidence of its infection was found in Asian badger, Meles leucurus (2/2) and leopard cat, Prionailurus bengalensis (5/8) through SN tests, whereas there was no evidence in raccoon dog, water deer, Eurasian otter, and Korean hare based on the collected sera in this study. These findings might provide partial evidence for the possible circulation of FPV or its related viruses among wild leopard cat and Asian badger in Korea. There should be additional study to confirm this through direct detection of FPVs in the related animal samples.https://www.frontiersin.org/articles/10.3389/fvets.2021.650866/fullfeline parvovirusfeline panleukopenialeopard catAsian badgerserum neutralization |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Young Ji Kim Young Ji Kim Sun-Woo Yoon Sun-Woo Yoon Jin Ho Jang Jin Ho Jang Dae Gwin Jeong Dae Gwin Jeong Beom Jun Lee Hye Kwon Kim |
spellingShingle |
Young Ji Kim Young Ji Kim Sun-Woo Yoon Sun-Woo Yoon Jin Ho Jang Jin Ho Jang Dae Gwin Jeong Dae Gwin Jeong Beom Jun Lee Hye Kwon Kim Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger Frontiers in Veterinary Science feline parvovirus feline panleukopenia leopard cat Asian badger serum neutralization |
author_facet |
Young Ji Kim Young Ji Kim Sun-Woo Yoon Sun-Woo Yoon Jin Ho Jang Jin Ho Jang Dae Gwin Jeong Dae Gwin Jeong Beom Jun Lee Hye Kwon Kim |
author_sort |
Young Ji Kim |
title |
Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger |
title_short |
Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger |
title_full |
Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger |
title_fullStr |
Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger |
title_full_unstemmed |
Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger |
title_sort |
genetic characterization of feline parvovirus isolate fe–p2 in korean cat and serological evidence on its infection in wild leopard cat and asian badger |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Veterinary Science |
issn |
2297-1769 |
publishDate |
2021-05-01 |
description |
Feline parvovirus (FPV) is a small, non-enveloped, single-stranded DNA virus that infects cats. We recently isolated a feline parvovirus Fe–P2 strain from a dead stray cat in Iksan, 2017. Its partial genomic sequence (4,643 bases) was obtained, and phylogenetic analysis based on the VP2 nucleotide sequence showed that the FPV Fe-P2 strain was closely related to the FPV isolate Gigucheon in cat, 2017 (MN400978). In addition, we performed a serum neutralization (SN) test with the FPV isolates in various mammalian sera. These were from raccoon dog, water deer, Eurasian otter, Korean hare, leopard cat, and Asian badger, which were kindly provided by Chungnam Wild Animal Rescue Center. Notably, serological evidence of its infection was found in Asian badger, Meles leucurus (2/2) and leopard cat, Prionailurus bengalensis (5/8) through SN tests, whereas there was no evidence in raccoon dog, water deer, Eurasian otter, and Korean hare based on the collected sera in this study. These findings might provide partial evidence for the possible circulation of FPV or its related viruses among wild leopard cat and Asian badger in Korea. There should be additional study to confirm this through direct detection of FPVs in the related animal samples. |
topic |
feline parvovirus feline panleukopenia leopard cat Asian badger serum neutralization |
url |
https://www.frontiersin.org/articles/10.3389/fvets.2021.650866/full |
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