Regulation of G Protein-Coupled Receptors by Ubiquitination

Regulation of G Protein-Coupled Receptors by Ubiquitination

G protein-coupled receptors (GPCRs) comprise the largest family of membrane receptors that control many cellular processes and consequently often serve as drug targets. These receptors undergo a strict regulation by mechanisms such as internalization and desensitization, which are strongly influence...

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Bibliographic Details
Main Authors: Kamila Skieterska, Pieter Rondou, Kathleen Van Craenenbroeck
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
G protein-coupled receptors (GPCR)
ubiquitination
β-arrestin
deubiquitinating enzyme
E3 ubiquitin ligase
Online Access:http://www.mdpi.com/1422-0067/18/5/923

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