Changing Trends of Breast Cancer Survival in Sultanate of Oman
Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 year...
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doaj-1aaa4b9e531c4ebe9804d8ce897f5b0b2020-11-24T23:23:10ZengHindawi LimitedJournal of Oncology1687-84501687-84692011-01-01201110.1155/2011/316243316243Changing Trends of Breast Cancer Survival in Sultanate of OmanShiyam Kumar0Ikram A. Burney1Adel Al-Ajmi2Mansour S. Al-Moundhri3Medical Oncology Unit, Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), P.O. Box 35, Muscat 123, OmanMedical Oncology Unit, Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), P.O. Box 35, Muscat 123, OmanDepartment of Surgery, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), Muscat, OmanMedical Oncology Unit, Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), P.O. Box 35, Muscat 123, OmanBreast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (𝑃=.023), skin involvement (𝑃=.003), and stage at presentation (𝑃=.004) were significantly associated with overall survival. Skin involvement at presentation (𝑃=.003), T size (𝑃=.09), lymph node status (𝑃=.013), and stage (𝑃=.003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved.http://dx.doi.org/10.1155/2011/316243 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shiyam Kumar Ikram A. Burney Adel Al-Ajmi Mansour S. Al-Moundhri |
spellingShingle |
Shiyam Kumar Ikram A. Burney Adel Al-Ajmi Mansour S. Al-Moundhri Changing Trends of Breast Cancer Survival in Sultanate of Oman Journal of Oncology |
author_facet |
Shiyam Kumar Ikram A. Burney Adel Al-Ajmi Mansour S. Al-Moundhri |
author_sort |
Shiyam Kumar |
title |
Changing Trends of Breast Cancer Survival in Sultanate of Oman |
title_short |
Changing Trends of Breast Cancer Survival in Sultanate of Oman |
title_full |
Changing Trends of Breast Cancer Survival in Sultanate of Oman |
title_fullStr |
Changing Trends of Breast Cancer Survival in Sultanate of Oman |
title_full_unstemmed |
Changing Trends of Breast Cancer Survival in Sultanate of Oman |
title_sort |
changing trends of breast cancer survival in sultanate of oman |
publisher |
Hindawi Limited |
series |
Journal of Oncology |
issn |
1687-8450 1687-8469 |
publishDate |
2011-01-01 |
description |
Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (𝑃=.023), skin involvement (𝑃=.003), and stage at presentation (𝑃=.004) were significantly associated with overall survival. Skin involvement at presentation (𝑃=.003), T size (𝑃=.09), lymph node status (𝑃=.013), and stage (𝑃=.003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved. |
url |
http://dx.doi.org/10.1155/2011/316243 |
work_keys_str_mv |
AT shiyamkumar changingtrendsofbreastcancersurvivalinsultanateofoman AT ikramaburney changingtrendsofbreastcancersurvivalinsultanateofoman AT adelalajmi changingtrendsofbreastcancersurvivalinsultanateofoman AT mansoursalmoundhri changingtrendsofbreastcancersurvivalinsultanateofoman |
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