Changing Trends of Breast Cancer Survival in Sultanate of Oman

Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 year...

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Main Authors: Shiyam Kumar, Ikram A. Burney, Adel Al-Ajmi, Mansour S. Al-Moundhri
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2011/316243
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spelling doaj-1aaa4b9e531c4ebe9804d8ce897f5b0b2020-11-24T23:23:10ZengHindawi LimitedJournal of Oncology1687-84501687-84692011-01-01201110.1155/2011/316243316243Changing Trends of Breast Cancer Survival in Sultanate of OmanShiyam Kumar0Ikram A. Burney1Adel Al-Ajmi2Mansour S. Al-Moundhri3Medical Oncology Unit, Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), P.O. Box 35, Muscat 123, OmanMedical Oncology Unit, Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), P.O. Box 35, Muscat 123, OmanDepartment of Surgery, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), Muscat, OmanMedical Oncology Unit, Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University (SQU), P.O. Box 35, Muscat 123, OmanBreast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (𝑃=.023), skin involvement (𝑃=.003), and stage at presentation (𝑃=.004) were significantly associated with overall survival. Skin involvement at presentation (𝑃=.003), T size (𝑃=.09), lymph node status (𝑃=.013), and stage (𝑃=.003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved.http://dx.doi.org/10.1155/2011/316243
collection DOAJ
language English
format Article
sources DOAJ
author Shiyam Kumar
Ikram A. Burney
Adel Al-Ajmi
Mansour S. Al-Moundhri
spellingShingle Shiyam Kumar
Ikram A. Burney
Adel Al-Ajmi
Mansour S. Al-Moundhri
Changing Trends of Breast Cancer Survival in Sultanate of Oman
Journal of Oncology
author_facet Shiyam Kumar
Ikram A. Burney
Adel Al-Ajmi
Mansour S. Al-Moundhri
author_sort Shiyam Kumar
title Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_short Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_full Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_fullStr Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_full_unstemmed Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_sort changing trends of breast cancer survival in sultanate of oman
publisher Hindawi Limited
series Journal of Oncology
issn 1687-8450
1687-8469
publishDate 2011-01-01
description Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (𝑃=.023), skin involvement (𝑃=.003), and stage at presentation (𝑃=.004) were significantly associated with overall survival. Skin involvement at presentation (𝑃=.003), T size (𝑃=.09), lymph node status (𝑃=.013), and stage (𝑃=.003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved.
url http://dx.doi.org/10.1155/2011/316243
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