An Investigation Into the Role of Osteocalcin in Human Arterial Smooth Muscle Cell Calcification

An Investigation Into the Role of Osteocalcin in Human Arterial Smooth Muscle Cell Calcification

Osteocalcin (OCN) is a bone-derived protein that is detected within human calcified vascular tissue. Calcification is particularly prevalent in chronic kidney disease (CKD) patients but the role of OCN in calcification, whether active or passive, has not been elucidated. Part 1: The relationship bet...

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Bibliographic Details
Main Authors: Sophie A. Millar, Stephen G. John, Christopher W. McIntyre, Vera Ralevic, Susan I. Anderson, Saoirse E. O'Sullivan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
osteocalcin
calcification
CKD
vascular
mineralization
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00369/full

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