Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both?
Abstract Fine-mapping to identify causal variants in genome-wide association studies remains challenging. A recent study provides guidance for future research.
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-06-01
|
| Series: | Genome Biology |
| Online Access: | http://link.springer.com/article/10.1186/s13059-017-1255-6 |
| id |
doaj-1ab886d694e1468c8eb799b2e9d33fb6 |
|---|---|
| record_format |
Article |
| spelling |
doaj-1ab886d694e1468c8eb799b2e9d33fb62020-11-25T00:35:07ZengBMCGenome Biology1474-760X2017-06-011811310.1186/s13059-017-1255-6Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both?Zhaoming Wang0Nilanjan Chatterjee1Department of Computational Biology, St. Jude Children’s Research HospitalDepartment of Biostatistics, Bloomberg School of Public Health and Department of Oncology, School of Medicine, Johns Hopkins UniversityAbstract Fine-mapping to identify causal variants in genome-wide association studies remains challenging. A recent study provides guidance for future research.http://link.springer.com/article/10.1186/s13059-017-1255-6 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Zhaoming Wang Nilanjan Chatterjee |
| spellingShingle |
Zhaoming Wang Nilanjan Chatterjee Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? Genome Biology |
| author_facet |
Zhaoming Wang Nilanjan Chatterjee |
| author_sort |
Zhaoming Wang |
| title |
Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? |
| title_short |
Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? |
| title_full |
Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? |
| title_fullStr |
Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? |
| title_full_unstemmed |
Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? |
| title_sort |
increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both? |
| publisher |
BMC |
| series |
Genome Biology |
| issn |
1474-760X |
| publishDate |
2017-06-01 |
| description |
Abstract Fine-mapping to identify causal variants in genome-wide association studies remains challenging. A recent study provides guidance for future research. |
| url |
http://link.springer.com/article/10.1186/s13059-017-1255-6 |
| work_keys_str_mv |
AT zhaomingwang increasingmappingprecisionofgenomewideassociationstudiestogenotypeandimputesequenceorboth AT nilanjanchatterjee increasingmappingprecisionofgenomewideassociationstudiestogenotypeandimputesequenceorboth |
| _version_ |
1725310244061446144 |