miR-150 promotes human breast cancer growth and malignant behavior by targeting the pro-apoptotic purinergic P2X7 receptor.

miR-150 promotes human breast cancer growth and malignant behavior by targeting the pro-apoptotic purinergic P2X7 receptor.

The P2X7 receptor regulates cell growth through mediation of apoptosis. Low level expression of P2X7 has been linked to cancer development because tumor cells harboring a defective P2X7 mechanism can escape P2X7 pro-apoptotic control. microRNAs (miRNAs) function as negative regulators of post-transc...

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Bibliographic Details
Main Authors: Songyin Huang, Yongsong Chen, Wei Wu, Nengyong Ouyang, Jianing Chen, Hongyu Li, Xiaoqiang Liu, Fengxi Su, Ling Lin, Yandan Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3846619?pdf=render

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http://europepmc.org/articles/PMC3846619?pdf=render

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