Peptic Ulcer Disease Associated with Helicobacter pylori Infection

Peptic Ulcer Disease Associated with Helicobacter pylori Infection

Although the global prevalence of peptic ulcer disease (PUD) is decreasing, PUD is still one of the most common upper gastro-intestinal diseases in the world due to Helicobacter pylori infection and increased use of non-steroidal anti-inflammatory drugs. In Korea, the prevalence of H. pylori infecti...

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Bibliographic Details
Main Authors: Se-Hwan Yeo, Chang-Hun Yang
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2016-06-01
Series:The Korean Journal of Gastroenterology
Subjects:
Helicobacter pylori
Peptic ulcer
Prevalence
Epidemiology
Therapy
Online Access:http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2016.67.6.289
Description
Summary:Although the global prevalence of peptic ulcer disease (PUD) is decreasing, PUD is still one of the most common upper gastro-intestinal diseases in the world due to Helicobacter pylori infection and increased use of non-steroidal anti-inflammatory drugs. In Korea, the prevalence of H. pylori infection is also declining, but it is still the major cause of PUD. The outcomes of H. pylori infection are caused by imbalances between bacterial virulence factors, host factors, and environmental influences. In this review, we describe the prevalence trends of H. pylori infection in Korea, the mechanism of H. pylori infection-related PUD, and treatment strategies. (Korean J Gastroenterol 2016;67:289-299)
ISSN:1598-9992

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