Early and transient alteration of adenosine A2A receptor signaling in a mouse model of Huntington disease
Huntington Disease (HD) is characterized by choreic involuntary movements and striatal vulnerability. A2A receptors expressed on GABAergic striatal neurons have been suggested to play a pathogenetic role. Previous data demonstrated the presence of an aberrant alteration of A2A receptor-dependent ade...
Main Authors: | Alessia Tarditi, Alessandra Camurri, Katia Varani, Pier Andrea Borea, Ben Woodman, Gillian Bates, Elena Cattaneo, Maria P. Abbracchio |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-07-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996106000180 |
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