Myocardial perfusion scintigraphy fi ndings in patients with mild coronary atherosclerotic lesions on coronary angiography

• Main Authors: Zeki Dostbil, Habib Çil, Ebru Öntürk Tekbas, Zuhal Arıtürk Atılgan, Yahya İslamoğlu, Yusuf Dağ, Bekir Tasdemir
• Format: Article
• Language: English
• Published: Dicle University Medical School 2010-09-01
• Series: Dicle Medical Journal
• Subjects: coronary artery disease; myocardial ischemia; myocardial perfusion imaging
• Online Access: http://www.dicle.edu.tr/fakulte/tip/dergi/yayin/373/16.pdf
• ISSN: 1300-2945; 1308-9889

Objectives: Myocardial perfusion scintigraphy (MPS) iswidely used in functional assessment of myocardial per-fusion. But, some study results are in contradiction withseverity of coronary artery disease detected by coronaryangiography (CA). It is frequently encountered case thatCA is completely normal whereas MPS describes isch-emia. In this study, we aimed to investigate whether mildatherosclerotic lesions cause ischemia.Materials and methods: MPS with 99mTc-MIBI was per-formed in 52 patients who applied to cardiology clinics forhistory of chest pain and underwent diagnostic CA within3 months.Results: In 22 of 52 patients with mild atherosclerotic le-sions, ischemia in various degrees was detected on MPS.In statistical analysis, any signifi cant relationship was notfound between ischemia and gender, hypertension, DM,dyslipidemia, smoking, mitral valve insuffi ciency, left ven-tricular hypertrophy, exercise testing result and affectedcoronary artery.Conclusion: Our study fi ndings have shown that mild ath-erosclerotic lesions even at very early stage may causemyocardial ischemia