Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells.

Mesenchymal stem cells (MSCs) are a promising cell population for cell-based bone repair due to their proliferative potential, ability to differentiate into bone-forming osteoblasts, and their secretion of potent trophic factors that stimulate angiogenesis and neovascularization. To promote bone hea...

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Bibliographic Details
Main Authors: Allison I Hoch, Bernard Y Binder, Damian C Genetos, J Kent Leach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3334972?pdf=render