Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors

Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has...

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Main Authors: Bettina Neumann, Ulla Wollenberger
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/13/3692
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spelling doaj-1b2382663acd48cea9d159c5d6e22f6d2020-11-25T03:07:48ZengMDPI AGSensors1424-82202020-07-01203692369210.3390/s20133692Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on SemiconductorsBettina Neumann0Ulla Wollenberger1Institute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, GermanyInstitute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, GermanyHeme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof.https://www.mdpi.com/1424-8220/20/13/3692electrochemical biosensorshemeperoxidasessemiconductorsperoxidase mimics
collection DOAJ
language English
format Article
sources DOAJ
author Bettina Neumann
Ulla Wollenberger
spellingShingle Bettina Neumann
Ulla Wollenberger
Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors
Sensors
electrochemical biosensors
heme
peroxidases
semiconductors
peroxidase mimics
author_facet Bettina Neumann
Ulla Wollenberger
author_sort Bettina Neumann
title Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors
title_short Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors
title_full Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors
title_fullStr Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors
title_full_unstemmed Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors
title_sort electrochemical biosensors employing natural and artificial heme peroxidases on semiconductors
publisher MDPI AG
series Sensors
issn 1424-8220
publishDate 2020-07-01
description Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof.
topic electrochemical biosensors
heme
peroxidases
semiconductors
peroxidase mimics
url https://www.mdpi.com/1424-8220/20/13/3692
work_keys_str_mv AT bettinaneumann electrochemicalbiosensorsemployingnaturalandartificialhemeperoxidasesonsemiconductors
AT ullawollenberger electrochemicalbiosensorsemployingnaturalandartificialhemeperoxidasesonsemiconductors
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