Platelet Microparticles Enriched in miR-223 Reduce ICAM-1-Dependent Vascular Inflammation in Septic Conditions

Platelet Microparticles Enriched in miR-223 Reduce ICAM-1-Dependent Vascular Inflammation in Septic Conditions

In the process of sepsis, activated platelets shed microvesicles containing microRNAs (miRNAs), which can be internalized by distinct recipient cells in circulation, consequently eliciting a potent capability to regulate their cellular functions in different diseases. In the present study, activated...

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Bibliographic Details
Main Authors: Bernadett Szilágyi, Zsolt Fejes, Ágnes Rusznyák, Ferenc Fenyvesi, Marianna Pócsi, Sándor Halmi, Zoltán Griger, Satya P. Kunapuli, János Kappelmayer, Béla Nagy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physiology
Subjects:
platelet
endothelial cell
microRNA
miR-223
sepsis
microparticle
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.658524/full

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