HATRIC-based identification of receptors for orphan ligands
Technologies for identifying receptor-ligand pairs on living cells at physiological conditions remain scarce. Here, the authors develop a mass spectrometry-based ligand receptor capture technology that can identify receptors for a diverse range of ligands at physiological pH with as few as a million...
Main Authors: | Nadine Sobotzki, Michael A. Schafroth, Alina Rudnicka, Anika Koetemann, Florian Marty, Sandra Goetze, Yohei Yamauchi, Erick M. Carreira, Bernd Wollscheid |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-03936-z |
Similar Items
-
Ubiquitin in Influenza Virus Entry and Innate Immunity
by: Alina Rudnicka, et al.
Published: (2016-10-01) -
Identification of an endogenous ligand bound to a native orphan nuclear receptor.
by: Xiaohui Yuan, et al.
Published: (2009-01-01) -
Systematic screening of Drosophila deficiency mutations for embryonic phenotypes and orphan receptor ligands.
by: Ashley P Wright, et al.
Published: (2010-08-01) -
Development of new <it>in silico</it> methods to identify ligands for orphan GPCR
by: Rognan Didier, et al.
Published: (2008-03-01) -
A Mass Spectrometry Approach to Ligand Identification for Orphan Fly and Human Nuclear Receptors
by: Pardee, Keith Ian
Published: (2010)