A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data

A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data

Abstract Background Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms that act during cancer development. The neutral mutational process is very complex: whole-genome analyses have revealed tha...

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Bibliographic Details
Main Authors: Johanna Bertl, Qianyun Guo, Malene Juul, Søren Besenbacher, Morten Muhlig Nielsen, Henrik Hornshøj, Jakob Skou Pedersen, Asger Hobolth
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Bioinformatics
Subjects:
Multinomial logistic regression
Site-specific model
Somatic cancer mutations
Online Access:http://link.springer.com/article/10.1186/s12859-018-2141-2

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