Noninvasive Detection of TMPRSS2:ERG Fusion Transcripts in the Urine of Men with Prostate Cancer

Noninvasive Detection of TMPRSS2:ERG Fusion Transcripts in the Urine of Men with Prostate Cancer

We recently reported the identification of recurrent gene fusions in the majority of prostate cancers involving the 5V untranslated region of the androgenregulated gene TMPRSS2, the ETS family members ERG, ETV1, ETV4. Here we report the noninvasive detection of these gene fusions in the urine of pa...

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Bibliographic Details
Main Authors: Bharathi Laxman, Scott A. Tomlins, Rohit Mehra, David S. Morris, Lei Wang, Beth E. Helgeson, Rajal B. Shah, Mark A. Rubin, John T. Wei, Arul M. Chinnaiyan
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Gene fusions
prostate cancer
noninvasive detection
urine
quantitative PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800928

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http://www.sciencedirect.com/science/article/pii/S1476558606800928

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