Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients

Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients

Exposure-response<b> </b>and clinical outcome (CO) model for inhaled budesonide/formoterol was developed to quantify the relationship among pharmacokinetics (PK), pharmacodynamics (PD) and CO of the drugs and evaluate the covariate effect on model parameters. Sputum eosinophils cationic...

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Bibliographic Details
Main Authors: Hyun-moon Back, Jong Bong Lee, Anhye Kim, Seon-Jong Park, Junyeong Kim, Jung-woo Chae, Seung Soo Sheen, Leonid Kagan, Hae-Sim Park, Young-Min Ye, Hwi-yeol Yun
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
moderate asthma
population analysis
budesonide/formoterol
asthma control test
dose optimization
Online Access:https://www.mdpi.com/1999-4923/12/4/336

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