Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration
In recent years remarkable efforts have been made to produce artificial bone through tissue engineering techniques. Silk fibroin (SF) and hydroxyapatite (HA) have been used in bone tissue regeneration as biomaterials due to mechanical properties of SF and biocompatibility of HA. There has been growi...
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doaj-1b839ca5cf2d4447b51ae066d14eaa922021-09-20T12:43:21ZengTaylor & Francis GroupScience and Technology of Advanced Materials1468-69961878-55142020-01-0121124226610.1080/14686996.2020.17485201748520Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regenerationMuhammad Saleem0Sidra Rasheed1Chen Yougen2Shenzhen University, Nanshan DistrictUniversity of KotliShenzhen University, Nanshan DistrictIn recent years remarkable efforts have been made to produce artificial bone through tissue engineering techniques. Silk fibroin (SF) and hydroxyapatite (HA) have been used in bone tissue regeneration as biomaterials due to mechanical properties of SF and biocompatibility of HA. There has been growing interest in developing SF/HA composites to reduce bone defects. In this regard, several attempts have been made to study the biocompatibility and osteoconductive properties of this material. This article overviews the recent advance from last few decades in terms of the preparative methods and application of SF/HA in bone regeneration. Its first part is related to SF that presents the most common sources, preparation methods and comparison of SF with other biomaterials. The second part illustrates the importance of HA by providing information about its production and properties. The third part presents comparative studies of SF/HA composites with different concentrations of HA along with methods of preparation of composites and their applications.http://dx.doi.org/10.1080/14686996.2020.1748520silk fibroinhydroxyapatitescaffoldbone regenerationbiomaterials |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Muhammad Saleem Sidra Rasheed Chen Yougen |
spellingShingle |
Muhammad Saleem Sidra Rasheed Chen Yougen Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration Science and Technology of Advanced Materials silk fibroin hydroxyapatite scaffold bone regeneration biomaterials |
author_facet |
Muhammad Saleem Sidra Rasheed Chen Yougen |
author_sort |
Muhammad Saleem |
title |
Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration |
title_short |
Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration |
title_full |
Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration |
title_fullStr |
Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration |
title_full_unstemmed |
Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration |
title_sort |
silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration |
publisher |
Taylor & Francis Group |
series |
Science and Technology of Advanced Materials |
issn |
1468-6996 1878-5514 |
publishDate |
2020-01-01 |
description |
In recent years remarkable efforts have been made to produce artificial bone through tissue engineering techniques. Silk fibroin (SF) and hydroxyapatite (HA) have been used in bone tissue regeneration as biomaterials due to mechanical properties of SF and biocompatibility of HA. There has been growing interest in developing SF/HA composites to reduce bone defects. In this regard, several attempts have been made to study the biocompatibility and osteoconductive properties of this material. This article overviews the recent advance from last few decades in terms of the preparative methods and application of SF/HA in bone regeneration. Its first part is related to SF that presents the most common sources, preparation methods and comparison of SF with other biomaterials. The second part illustrates the importance of HA by providing information about its production and properties. The third part presents comparative studies of SF/HA composites with different concentrations of HA along with methods of preparation of composites and their applications. |
topic |
silk fibroin hydroxyapatite scaffold bone regeneration biomaterials |
url |
http://dx.doi.org/10.1080/14686996.2020.1748520 |
work_keys_str_mv |
AT muhammadsaleem silkfibroinhydroxyapatitescaffoldahighlycompatiblematerialforboneregeneration AT sidrarasheed silkfibroinhydroxyapatitescaffoldahighlycompatiblematerialforboneregeneration AT chenyougen silkfibroinhydroxyapatitescaffoldahighlycompatiblematerialforboneregeneration |
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1717374481478975488 |