Unexpected hearing improvement after treatment with valganciclovir in a child with congenital cytomegalovirus infection

A 32-week preterm-born male with symptomatic congenital cytomegalovirus infection was treated with valganciclovir. He was also affected by congenital severe bilateral hearing loss and, unexpectedly, a normalization of the hearing threshold was reached at one year of age. The improvement of hearing l...

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Bibliographic Details
Main Authors: Silvia Palma, Laura Mazzoni, Maria Federica Roversi, Cecilia Botti, Daniele Monzani, Alberto Berardi, Elisabetta Genovese
Format: Article
Language:English
Published: Pensoft Publishers 2021-04-01
Series:Folia Medica
Subjects:
CMV
Online Access:https://foliamedica.bg/article/54665/download/pdf/
Description
Summary:A 32-week preterm-born male with symptomatic congenital cytomegalovirus infection was treated with valganciclovir. He was also affected by congenital severe bilateral hearing loss and, unexpectedly, a normalization of the hearing threshold was reached at one year of age. The improvement of hearing level in relationship with both the late development of the auditory system and the administration of antiviral therapy is discussed. This case also highlights the importance of early diagnosis of congenital cytomegalovirus associated with close follow-up.
ISSN:1314-2143