Stages in the evolution of the Hardy-Weinberg law
The Hardy-Weinberg law has been used widely for about one hundred years with little question as to the foundations laid down by its originators. The basic assumption of random mating, that is choice of mates by a process akin to that of a lottery, was shown to produce genotypic proportions following...
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Sociedade Brasileira de Genética
2006-01-01
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doaj-1b9abde6c01c411ab500dc74fc98f5e62020-11-25T01:46:18ZengSociedade Brasileira de GenéticaGenetics and Molecular Biology1415-47571678-46852006-01-0129458959410.1590/S1415-47572006000400001Stages in the evolution of the Hardy-Weinberg lawAlan E. StarkThe Hardy-Weinberg law has been used widely for about one hundred years with little question as to the foundations laid down by its originators. The basic assumption of random mating, that is choice of mates by a process akin to that of a lottery, was shown to produce genotypic proportions following the "binomial-square" rule, the so-called Hardy-Weinberg proportions (HWP). It has been assumed by many that random mating was the only way of pairing genes capable of producing HWP. However it has been shown that HWP can be obtained and maintained by non-random mating. The steps along the way to this revelation and some implications are reviewed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000400001Hardy-Weinberg lawnon-random mating |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Alan E. Stark |
spellingShingle |
Alan E. Stark Stages in the evolution of the Hardy-Weinberg law Genetics and Molecular Biology Hardy-Weinberg law non-random mating |
author_facet |
Alan E. Stark |
author_sort |
Alan E. Stark |
title |
Stages in the evolution of the Hardy-Weinberg law |
title_short |
Stages in the evolution of the Hardy-Weinberg law |
title_full |
Stages in the evolution of the Hardy-Weinberg law |
title_fullStr |
Stages in the evolution of the Hardy-Weinberg law |
title_full_unstemmed |
Stages in the evolution of the Hardy-Weinberg law |
title_sort |
stages in the evolution of the hardy-weinberg law |
publisher |
Sociedade Brasileira de Genética |
series |
Genetics and Molecular Biology |
issn |
1415-4757 1678-4685 |
publishDate |
2006-01-01 |
description |
The Hardy-Weinberg law has been used widely for about one hundred years with little question as to the foundations laid down by its originators. The basic assumption of random mating, that is choice of mates by a process akin to that of a lottery, was shown to produce genotypic proportions following the "binomial-square" rule, the so-called Hardy-Weinberg proportions (HWP). It has been assumed by many that random mating was the only way of pairing genes capable of producing HWP. However it has been shown that HWP can be obtained and maintained by non-random mating. The steps along the way to this revelation and some implications are reviewed. |
topic |
Hardy-Weinberg law non-random mating |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000400001 |
work_keys_str_mv |
AT alanestark stagesintheevolutionofthehardyweinberglaw |
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