Antimicrobial evaluation of diaminothiazoloylbenzothiazoles

Antimicrobial evaluation of diaminothiazoloylbenzothiazoles

A series of 2-(4-amino-2-aryl/alkylaminothiazol-5-oyl) benzothiazole derivatives were synthesized from amidinothioureas and 2-(2-bromoacetyl)benzothiazole with triethylamine. Their structures were established on the basis of IR, 1H NMR, 13C NMR and mass spectral analyses. All the synthesized compoun...

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Main Authors: A. Yardily, V. Anu Danie, Bojaxa A. Rosy, T.F. Abbs Fen Reji
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Saudi Chemical Society
Subjects:
Benzothiazole
Antibacterial activity
Antifungal activity
Antituberculosis activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312000920
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spelling doaj-1b9e2a2faeca42c6925820bb181e8b622020-11-24T23:56:50ZengElsevierJournal of Saudi Chemical Society1319-61032016-05-0120327828110.1016/j.jscs.2012.07.005Antimicrobial evaluation of diaminothiazoloylbenzothiazolesA. Yardily0V. Anu Danie1Bojaxa A. Rosy2T.F. Abbs Fen Reji3Department of Chemistry and Research Centre, Scott Christian College (Autonomous), Nagercoil, Tamilnadu, IndiaDepartment of Chemistry and Research Centre, Nesamony Memorial Christian College, Marthandam, Tamilnadu, IndiaDepartment of Botany and Research Centre, Holy Cross College, Nagercoil, Tamilnadu, IndiaDepartment of Chemistry and Research Centre, Nesamony Memorial Christian College, Marthandam, Tamilnadu, IndiaA series of 2-(4-amino-2-aryl/alkylaminothiazol-5-oyl) benzothiazole derivatives were synthesized from amidinothioureas and 2-(2-bromoacetyl)benzothiazole with triethylamine. Their structures were established on the basis of IR, 1H NMR, 13C NMR and mass spectral analyses. All the synthesized compounds were screened for their antibacterial, antifungal and antimycobacterial potential. All the compounds showed significant activity against the microorganisms tested.http://www.sciencedirect.com/science/article/pii/S1319610312000920BenzothiazoleAntibacterial activityAntifungal activityAntituberculosis activity
collection DOAJ
language English
format Article
sources DOAJ
author A. Yardily
V. Anu Danie
Bojaxa A. Rosy
T.F. Abbs Fen Reji
spellingShingle A. Yardily
V. Anu Danie
Bojaxa A. Rosy
T.F. Abbs Fen Reji
Antimicrobial evaluation of diaminothiazoloylbenzothiazoles
Journal of Saudi Chemical Society
Benzothiazole
Antibacterial activity
Antifungal activity
Antituberculosis activity
author_facet A. Yardily
V. Anu Danie
Bojaxa A. Rosy
T.F. Abbs Fen Reji
author_sort A. Yardily
title Antimicrobial evaluation of diaminothiazoloylbenzothiazoles
title_short Antimicrobial evaluation of diaminothiazoloylbenzothiazoles
title_full Antimicrobial evaluation of diaminothiazoloylbenzothiazoles
title_fullStr Antimicrobial evaluation of diaminothiazoloylbenzothiazoles
title_full_unstemmed Antimicrobial evaluation of diaminothiazoloylbenzothiazoles
title_sort antimicrobial evaluation of diaminothiazoloylbenzothiazoles
publisher Elsevier
series Journal of Saudi Chemical Society
issn 1319-6103
publishDate 2016-05-01
description A series of 2-(4-amino-2-aryl/alkylaminothiazol-5-oyl) benzothiazole derivatives were synthesized from amidinothioureas and 2-(2-bromoacetyl)benzothiazole with triethylamine. Their structures were established on the basis of IR, 1H NMR, 13C NMR and mass spectral analyses. All the synthesized compounds were screened for their antibacterial, antifungal and antimycobacterial potential. All the compounds showed significant activity against the microorganisms tested.
topic Benzothiazole
Antibacterial activity
Antifungal activity
Antituberculosis activity
url http://www.sciencedirect.com/science/article/pii/S1319610312000920
work_keys_str_mv AT ayardily antimicrobialevaluationofdiaminothiazoloylbenzothiazoles
AT vanudanie antimicrobialevaluationofdiaminothiazoloylbenzothiazoles
AT bojaxaarosy antimicrobialevaluationofdiaminothiazoloylbenzothiazoles
AT tfabbsfenreji antimicrobialevaluationofdiaminothiazoloylbenzothiazoles
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