RhoE deficiency produces postnatal lethality, profound motor deficits and neurodevelopmental delay in mice.

RhoE deficiency produces postnatal lethality, profound motor deficits and neurodevelopmental delay in mice.

Rnd proteins are a subfamily of Rho GTPases involved in the control of actin cytoskeleton dynamics and other cell functions such as motility, proliferation and survival. Unlike other members of the Rho family, Rnd proteins lack GTPase activity and therefore remain constitutively active. We have rece...

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Bibliographic Details
Main Authors: Enric Mocholí, Begoña Ballester-Lurbe, Gloria Arqué, Enric Poch, Blanca Peris, Consuelo Guerri, Mara Dierssen, Rosa M Guasch, José Terrado, Ignacio Pérez-Roger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21552537/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21552537/?tool=EBI

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