Genetics of Tinnitus: Time to Biobank Phantom Sounds
Tinnitus is a common phantom sensation resulting most often from sensory deprivation, and for which little knowledge on the molecular mechanisms exists. While the existing evidence for a genetic influence on the condition has been until now sparse and underpowered, recent data suggest that specific...
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doaj-1ba495189cc24ba78e51a0873af808422020-11-24T22:07:18ZengFrontiers Media S.A.Frontiers in Genetics1664-80212017-09-01810.3389/fgene.2017.00110294129Genetics of Tinnitus: Time to Biobank Phantom SoundsChristopher R. Cederroth0Anna K. Kähler1Patrick F. Sullivan2Patrick F. Sullivan3Patrick F. Sullivan4Jose A. Lopez-Escamez5Jose A. Lopez-Escamez6Experimental Audiology, Department of Physiology and Pharmacology, Karolinska InstitutetStockholm, SwedenDepartment of Molecular Epidemiology and Biostatistics, Karolinska InstitutetStockholm, SwedenDepartment of Molecular Epidemiology and Biostatistics, Karolinska InstitutetStockholm, SwedenDepartment of Genetics, University of North Carolina, Chapel HillNC, United StatesDepartment of Psychiatry, University of North Carolina, Chapel HillNC, United StatesOtology & Neurotology Group, Department of Genomic Medicine, Pfizer-Universidad de Granada-Junta de Andalucía Centre for Genomics and Oncology Research (GENyO)Granada, SpainDepartment of Otolaryngology, Instituto de Investigación Biosanitaria ibs.GRANADA, Hospital Virgen de las Nieves, Universidad de GranadaGranada, SpainTinnitus is a common phantom sensation resulting most often from sensory deprivation, and for which little knowledge on the molecular mechanisms exists. While the existing evidence for a genetic influence on the condition has been until now sparse and underpowered, recent data suggest that specific forms of tinnitus have a strong genetic component revealing that not all tinnitus percepts are alike, at least in how they are genetically driven. These new findings pave the way for a better understanding on how phantom sensations are molecularly driven and call for international biobanking efforts.http://journal.frontiersin.org/article/10.3389/fgene.2017.00110/fulltinnitusgeneticsheritabilitysubtypeneuropsychiatryGWAS (genome-wide association study) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Christopher R. Cederroth Anna K. Kähler Patrick F. Sullivan Patrick F. Sullivan Patrick F. Sullivan Jose A. Lopez-Escamez Jose A. Lopez-Escamez |
spellingShingle |
Christopher R. Cederroth Anna K. Kähler Patrick F. Sullivan Patrick F. Sullivan Patrick F. Sullivan Jose A. Lopez-Escamez Jose A. Lopez-Escamez Genetics of Tinnitus: Time to Biobank Phantom Sounds Frontiers in Genetics tinnitus genetics heritability subtype neuropsychiatry GWAS (genome-wide association study) |
author_facet |
Christopher R. Cederroth Anna K. Kähler Patrick F. Sullivan Patrick F. Sullivan Patrick F. Sullivan Jose A. Lopez-Escamez Jose A. Lopez-Escamez |
author_sort |
Christopher R. Cederroth |
title |
Genetics of Tinnitus: Time to Biobank Phantom Sounds |
title_short |
Genetics of Tinnitus: Time to Biobank Phantom Sounds |
title_full |
Genetics of Tinnitus: Time to Biobank Phantom Sounds |
title_fullStr |
Genetics of Tinnitus: Time to Biobank Phantom Sounds |
title_full_unstemmed |
Genetics of Tinnitus: Time to Biobank Phantom Sounds |
title_sort |
genetics of tinnitus: time to biobank phantom sounds |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Genetics |
issn |
1664-8021 |
publishDate |
2017-09-01 |
description |
Tinnitus is a common phantom sensation resulting most often from sensory deprivation, and for which little knowledge on the molecular mechanisms exists. While the existing evidence for a genetic influence on the condition has been until now sparse and underpowered, recent data suggest that specific forms of tinnitus have a strong genetic component revealing that not all tinnitus percepts are alike, at least in how they are genetically driven. These new findings pave the way for a better understanding on how phantom sensations are molecularly driven and call for international biobanking efforts. |
topic |
tinnitus genetics heritability subtype neuropsychiatry GWAS (genome-wide association study) |
url |
http://journal.frontiersin.org/article/10.3389/fgene.2017.00110/full |
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