Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study

Objectives: To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).

Bibliographic Details
Main Authors: Bharti Mackness, Judit Marsillach, Robert S. Elkeles, Ian F. Godsland, Michael D. Feher, Michael B. Rubens, Marcus D. Flather, Steve E. Humphries, Jackie Cooper, Mike Mackness
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2012-0910
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spelling doaj-1ba9ada91fca42b4b3c22b6acfeeb83d2020-11-24T23:16:14ZengHindawi LimitedDisease Markers0278-02401875-86302012-01-0133210111210.3233/DMA-2012-0910Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT StudyBharti Mackness0Judit Marsillach1Robert S. Elkeles2Ian F. Godsland3Michael D. Feher4Michael B. Rubens5Marcus D. Flather6Steve E. Humphries7Jackie Cooper8Mike Mackness9Pontech Art, Calle De L’Argelagar, Tarragona, SpainMedicine (Division of Medical Genetics) and Genome Sciences, University of Washington, Seattle, WA, USAEndocrinology and Metabolic Medicine, Imperial College London, St Mary’s Hospital, London, UKEndocrinology and Metabolic Medicine, Imperial College London, St Mary’s Hospital, London, UKBeta Cell Unit, Chelsea and Westminster Hospital, London, UKCT Scanning Unit, Royal Brompton Hospital, London, UKClinical Trials and Evaluation Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, UKThe Rayne Institute, Royal Free and University College Medical School, London, UKThe Rayne Institute, Royal Free and University College Medical School, London, UKPontech Art, Calle De L’Argelagar, Tarragona, SpainObjectives: To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).http://dx.doi.org/10.3233/DMA-2012-0910
collection DOAJ
language English
format Article
sources DOAJ
author Bharti Mackness
Judit Marsillach
Robert S. Elkeles
Ian F. Godsland
Michael D. Feher
Michael B. Rubens
Marcus D. Flather
Steve E. Humphries
Jackie Cooper
Mike Mackness
spellingShingle Bharti Mackness
Judit Marsillach
Robert S. Elkeles
Ian F. Godsland
Michael D. Feher
Michael B. Rubens
Marcus D. Flather
Steve E. Humphries
Jackie Cooper
Mike Mackness
Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study
Disease Markers
author_facet Bharti Mackness
Judit Marsillach
Robert S. Elkeles
Ian F. Godsland
Michael D. Feher
Michael B. Rubens
Marcus D. Flather
Steve E. Humphries
Jackie Cooper
Mike Mackness
author_sort Bharti Mackness
title Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study
title_short Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study
title_full Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study
title_fullStr Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study
title_full_unstemmed Paraoxonase-1 Is Not Associated with Coronary Artery Calcification in Type 2 Diabetes: Results from the PREDICT Study
title_sort paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: results from the predict study
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2012-01-01
description Objectives: To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).
url http://dx.doi.org/10.3233/DMA-2012-0910
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