Synovial sarcoma of the stomach: case report and systematic review of the literature

Synovial sarcoma of the stomach: case report and systematic review of the literature

Synovial sarcoma is a rare mesenchymal malignant neoplasm that presents a specific t(X;18) translocation forming SS18(SYT)-SSX chimera gene. It is most commonly seen in soft tissues of the extremities. The digestive tract is an exceptional site of involvement. We report a case of primary gastric sy...

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Bibliographic Details
Main Authors: Martyna Kurpińska, Ewa Kaznowska, Anna Kruczak, Katarzyna Mularz, Agnieszka Adamczyk, Jarosław Długosz, Józef Gancarz, Janusz Ryś
Format: Article
Language:English
Published: Termedia Publishing House 2020-07-01
Series:Polish Journal of Pathology
Subjects:
synovial sarcoma
stomach
spindle cell neoplasm
cytokeratin.
Online Access:https://www.termedia.pl/Synovial-sarcoma-of-the-stomach-case-report-and-systematic-review-of-the-literature,55,41210,1,1.html
Description
Summary:Synovial sarcoma is a rare mesenchymal malignant neoplasm that presents a specific t(X;18) translocation forming SS18(SYT)-SSX chimera gene. It is most commonly seen in soft tissues of the extremities. The digestive tract is an exceptional site of involvement. We report a case of primary gastric synovial sarcoma in a 48-year-old female. Differential diagnosis of synovial sarcoma from other spindle cell, mesenchymal and cytokeratin-positive tumors is critical for the treatment and prognosis. Immunohistochemistry studies and molecular analysis are required to settle a proper diagnosis.
ISSN:1233-9687
2084-9869

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