Association study of relationships of polymorphisms in the miR-21, miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer

Association study of relationships of polymorphisms in the miR-21, miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer

Abstract Background miR-21, miR-26b, miR-221/222 and miR-126 play crucial roles in cervical cancer development. Studies have shown that polymorphisms in miRNA genes can affect miRNA expression, which might be associated with cancer development. Methods Ten single-nucleotide polymorphisms (SNPs) in t...

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Bibliographic Details
Main Authors: Jia Yang, Zhiling Yan, Yingying Wang, Jinmei Xu, Rui Li, Chuanyin Li, Shuyuan Liu, Li Shi, Yufeng Yao
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Cancer
Subjects:
Cervical intraepithelial neoplasia (CIN)
Cervical cancer (CC)
MiRNA
Single-nucleotide polymorphisms (SNPs)
Chinese population
Online Access:https://doi.org/10.1186/s12885-021-08743-2

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