Xanthomas Regression in an 8-Year-Old Boy Treated With Lomitapide

Xanthomas Regression in an 8-Year-Old Boy Treated With Lomitapide

This case reports on an 8-year-old boy with homozygous familial hypercholesterolemia with large tuberous xanthomas over his hands, elbows, buttocks, knees, and feet. Lomitapide 40 mg daily (steadily increased) was added to his classical lipid-lowering therapy. A 50% reduction in the thickness, hardn...

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Bibliographic Details
Main Authors: Genovefa Kolovou, MD, PhD, Aleksandros Tsoutsinos, MD, Irene Mastorakou, MD, MSc, PhD, Sophie Mavrogeni, MD, PhD, George Hatzigeorgiou, MD
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:JACC: Case Reports
Subjects:
colesevelam
ezetimibe
homozygous familial hypercholesterolemia
lomitapide
statins
Online Access:http://www.sciencedirect.com/science/article/pii/S2666084919302438
Description
Summary:This case reports on an 8-year-old boy with homozygous familial hypercholesterolemia with large tuberous xanthomas over his hands, elbows, buttocks, knees, and feet. Lomitapide 40 mg daily (steadily increased) was added to his classical lipid-lowering therapy. A 50% reduction in the thickness, hardness, size, and color intensity of xanthomas was reported after 2 years of treatment. (Level of Difficulty: Intermediate.)
ISSN:2666-0849

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